Table 4.
Cytokines | Time 0 (before SOC) | Time 1 (1 week after) | Time 2 (1 month after) |
---|---|---|---|
Proinflamatory | |||
IL-2 | 1.05 (1.05–1.05) | 1.05 (1.05–1.42) | 1.05 (1.05–1.05) |
IL-12 | 104.49 (35.97–104.49) | 104.49 (80.98–138.11) | 75.77 (10.45–104.49) |
IFN-ɤ | 55.25 (47.75–173.17) | 149 (47.75–250.31) | 47.75 (4.77–100.35)# |
Anti-inflammatory | |||
IL-4 | 0.15 (0.15–0.15) | 0.15 (0.15–7.07) | 0.15 (0.15–6.31) |
IL-10 | 165.01 (29.85–237.02) | 201.02 (29.85–298.54) | 201.02 (29.85–276.18) |
IL-13 | 1.72 (1.72–3.45) | 2.59 (1.72–8.75) | 2.59 (1.72–8.75) |
IL-5 | 4.75 (4.75–149.81) | 61.71 (47.46–101.89)* | 49.91 (29.01–59.42) |
Wilcoxon tests for paired samples were used to evaluate differences in concentrations across time.
Significant differences (p < 0.05) are indicated in bold for comparisons with time 0*, and time 1#.
IQR, interquartile ranges; SOC, standardized oral challenge.