Table 6.
Multivariable Cox analysis with genotype–ACEi treatment interaction for microalbuminuria and cardiovascular endpoints (without other covariates, reference: ACEi yes).
| New onset microalbuminuria Number of events = 98 |
Cardiovascular events Number of events = 112 |
|||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
| p.Glu936Asp° | 6.210 (2.563–15.044) | <0.0001 | 3.655 (1.445–9.242)) | 0.006 |
| ACEi therapy | 2.584 (1.648–4.052) | <0.0001 | 1.489 (1.007–2.200) | 0.046 |
| p.Glu936Asp*ACEi therapy | 0.096 (0.011–0.837) | 0.034 | 0.384 (0.071–2.073) | 0.266 |
°Recessive model. P values in bold are statistically significant.