Table 2.

Flow cytometric evaluation of expression of NADPH oxidase components in control and patient's neutrophils.

Patient no.	Defective component of NADPH oxidase	Signal (S)/noise (N) ratio for component staining		Gene involved
		S/N ratio for patient	S/N ratio for control
1	p47phox	4.71	11.42	NCF1
2	p47phox	3.23	5	NCF1
3	p47phox	3.19	11.11	NCF1
4	P22phox	1.45#	14.46	CYBB/CYBA
5	P22phox	1.95	72.21	CYBB/CYBA

*MFI of stained (S) to unstained (N) neutrophils in patients and controls.

^#Mother showed mosaic pattern after staining with anti-p22^phox antibodies indicating patient having defect in X-linked component, i.e., gp91^phox.