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. 2019 Aug 6;13:2745–2757. doi: 10.2147/DDDT.S213910

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© 2019 Zheng et al.

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Effects of liraglutide and telmisartan on the expression of AT1R, AT2R, AT1R/AT2R ratio, and ACE2 after AAC. (A and B) Protein levels of AT1R and AT2R were detected by Western blot assay. (C) AT1R/AT2R ratio was calculated from the intensity of each individual bands. (D) ACE2 expression in the intermyocardium and intracardiac vessels was determined using immunohistochemical staining and calculated as mean optical density (MOD) in the tissue section (magnification: 200; scale bars: 100 μm). Values are mean±SEM (n=6/group). *p<0.05 AAC vs Sham; ^#p<0.05 Lira or Telmi vs AAC.

Abbreviation: AAC, abdominal aortic constriction.