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. 2019 Aug 6;13:2745–2757. doi: 10.2147/DDDT.S213910

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© 2019 Zheng et al.

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Effects of liraglutide and telmisartan on the proliferation of myofibroblasts and the expression of Smads. (A) The numbers of myofibroblasts were determined by α-SMA positive cells (arrows) using immunohistochemistry. (B) Phosphorylated and total protein levels of Smad2 and Smad3 were detected by Western blot assay. (C and D) Protein levels of Smad4 and Smad7 were detected by Western blot assay. Values are mean±SEM (n=6/group). *p<0.05 AAC vs Sham; ^#p<0.05 Lira or Telmi vs AAC.

Abbreviation: AAC, abdominal aortic constriction.