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. 2019 Jul 9;125(4):431–448. doi: 10.1161/CIRCRESAHA.119.314817

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© 2019 The Authors.

Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 5. — Regulated transcript networks after acute and chronic hemodynamic stress. Unbiased clustering analysis of Ribo-seq and RNA-seq of DEGs 3h, 2d, and 2w after transverse aortic constriction (TAC) surgery. Different colors indicate different clusters. Lines of each gene are transparent, and the lines of average values are in bold in each cluster. Numbers indicate significant genes by RNA-seq or Ribo-seq in the cluster and the total number of genes within the cluster (n). Scale: scaled gene expression. cAMP indicates cyclic adenosine monophosphate; ECM, extracellular matrix; ER, endoplasmic reticulum; TCA, tricarboxylic acid cycle; and TGF, transforming growth factor.