Table I.

Total glutathione data of all groups (μM)

t [min]	Control	Amiodarone	P-value**	Amiodarone + Vit. C	Amiodarone + NAC	Amiodarone + Vit. E
1	584.2 ±91.2	150.5 ±87.1	< 0.0001	321.4 ±126.1 p*** < 0.0001	332.8 ±118.7 p*** < 0.0001	372.7 ±92.0 p*** < 0.0001
2	607.7 ±91.4	162.2 ±96.3	< 0.0001	334.3 ±134.1 p*** < 0.0001	345.7 ±125.6 p*** < 0.0001	386.8 ±95.2 p*** < 0.0001
3	627.0 ±88.2	176.3 ±104.7	< 0.0001	347.7 ±142.7 p*** < 0.0001	360.1 ±132.8 p*** < 0.0001	402.3 ±99.2 p*** < 0.0001
4	644.3 ±83.6	188.8 ±113.8	< 0.0001	363.6 ±151.5 p*** < 0.0001	375.5 ±140.0 p*** < 0.0001	419.7 ±104.4 p*** < 0.0001
5	659.4 ±77.4	205.4 ±122.5	< 0.0001	380.0 ±157.7 p*** < 0.0001	392.8 ±147.4 p*** < 0.0001	440.6 ±109.3 p*** < 0.0001
P-value*	< 0.0001	< 0.0001		< 0.0001	< 0.0001	< 0.0001

^*2-way ANOVA

^**comparison between control vs. amiodarone groups/Bonferroni adjusted Mann-Whitney U

^***comparison between groups vs. amiodarone group/Bonferroni adjusted Mann-Whitney U.

All data are presented as mean ± SD. The level of significance was taken as p < 0.05. t – time, Vit. C – vitamin C, NAC – N-acetyl cysteine, Vit. E – vitamin E.