TABLE 2.
Response and Remission Rates in the Intent-to-Treat Last Observation Carried Forward Sample
| Outcome | Cognitive- Behavioral Therapy (N=105) |
Escitalopram (N=105) |
Duloxetine (N=106) |
Total Sample (N=316) |
||||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | |
| Non-responsea | 32 | 30.5 | 26 | 24.8 | 21 | 19.8 | 79 | 25.0 |
| Partial responseb | 19 | 18.1 | 12 | 11.4 | 16 | 15.1 | 47 | 14.9 |
| Response without remissionc | 10 | 9.5 | 18 | 17.1 | 11 | 10.4 | 39 | 12.3 |
| Remissiond | 44 | 41.9 | 49 | 46.7 | 58 | 54.7 | 151 | 47.8 |
Endpoint Hamilton Depression Rating Scale (HAM-D) score <30% improved from baseline.
Endpoint HAM-D score 30%−49% improved from baseline.
Endpoint HAM-D score ≥50% reduction from baseline, without meeting remission criteria.
HAM-D score ≤7 at both week 10 and week 12 visits. (or final two ratings visits for noncompleters in the last observation carried forward sample).