Patient population: From October 2016 to May 2017, 72 pediatric patients underwent living-donor liver transplantation. Of the 60 patients with Bayley Scale of Infant Development-II (BSID-II) tests before transplantation in our initial cohort, 12 were excluded because of congenital heart disease, other operations (except Kasai), re-transplantation, or incoordination in the test. Sixty patients were initially studied in this experiment, and all were tested within a week before their operation. Half a year later, 2 cases were dead, with 1 patient dying from graft-versus-host reaction (GVHR) and 1 patient dying from multiple organ failure. One patient was excluded because of re-transplantation due to graft failure, and 3 patients had no re-examination half a year after transplantation. In total, 54 cases were included in the trial half a year after transplantation.