Table 2.
Comparison of clinical and laboratory characteristics in treatment and control groups (T test) on 1st, 3rd and 7th day after treatment
| Baseline characteristics | Days | Treatment group | Control group | P value |
|---|---|---|---|---|
| MAP (Mean Arterial Pressure) ± SD | 1st day | 97.2±21 | 92.6±17.7 | 0.2 |
| 3rd day | 92.9±16 | 100.4±15.4 | 0.01 | |
| 7th day | 93±14.3 | 89.2±13 | 0.1 | |
| Heart rate (beat/min) ± SD | 1st day | 99.7±26.2 | 107±26.7 | 0.1 |
| 3rd day | 89.9±20.7 | 96.7±23.5 | 0.1 | |
| 7th day | 86.8±20.4 | 91.3±20.8 | 0.2 | |
| Respiratory Rate (beat/min) ± SD | 1st day | 25.4±4 | 26±4.4 | 0.4 |
| 3rd day | 19.9±3.2 | 21.3±4.3 | 0.07 | |
| 7th day | 18.1±3.9 | 18.3±4.5 | 0.7 | |
| Temperature (°C) ± SD | 1st day | 38.5±1.1 | 38.5±1 | 0.7 |
| 3rd day | 37.7±0.7 | 37.9±0.7 | 0.2 | |
| 7th day | 37.3±0.6 | 37.3±0.6 | 0.8 | |
| Leukocyte count (per mm3) ± SD | 1st day | 14145.6±4759 | 15687.7±3899 | 0.06 |
| 3rd day | 11303.5±4408 | 13635±4013 | 0.004 | |
| 7th day | 10269.6±3446 | 11064.9±3588 | 0.2 | |
| Plasma Creatinine ± SD | 1st day | 1.2±0.5 | 1.2±0.6 | 0.9 |
| 3rd day | 1.2±0.6 | 1.1±0.8 | 0.8 | |
| 7th day | 1.2±0.7 | 1.2±0.8 | 0.9 | |
| Plasma urea± SD | 1st day | 30.2±10.8 | 26.5±11.2 | 0.07 |
| 3rd day | 29.1±11.3 | 25.9±11.4 | 0.1 | |
| 7th day | 29.4±13.3 | 25.8±12.7 | 0.1 | |
| Arterial blood pH± SD | 1st day | 7.4±1 | 7.4±1 | 0.8 |
| 3rd day | 7.3±0 | 7.4±0 | 0.6 | |
| 7th day | 7.3±0 | 7.3±0 | 0.8 | |
| Pressure of oxygen in arterial± SD | 1st day | 84.7±9.9 | 83.1±7.8 | 0.3 |
| 3rd day | 87.9±9.9 | 86.5±7.3 | 0.3 | |
| 7th day | 89.4±11.8 | 89.3±8.5 | 0.9 | |
| Oxygen saturation (SpO2) ± SD | 1st day | 92.1±6.3 | 89.7±6.4 | 0.052 |
| 3rd day | 94.5±6 | 92.7±6.3 | 0.1 | |
| 7th day | 95.1±7.4 | 94.7±6.9 | 0.8 | |
| Fraction of inspired oxygen (FiO2) ± SD | 1st day | 56±16.4 | 58.7±15.6 | 0.3 |
| 3rd day | 51.7±17.7 | 54.9±16.5 | 0.3 | |
| 7th day | 49.7±17.5 | 54.3±18 | 0.1 |