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. Author manuscript; available in PMC: 2019 Aug 12.
Published in final edited form as: Methods Mol Biol. 2010;640:115–138. doi: 10.1007/978-1-60761-688-7_6

Fig. 6.4.

Fig. 6.4.

Effect of dexamethasone concentration dependency on hepatocyte morphology and viability. Primary rat hepatocytes were cultured for 96 h under the stated dexamethasone (Dex) concentrations (nM) in the presence of a Matrigel overlay (×20 magnification). Arrows identify evidence of perturbed morphology: condensed cytoplasm and rounded-up cells, attributed to cytotoxicity. The tower right panel shows the relative level of LDH leakage associated with each Dex concentration. Reproduced from Experimental Cell Research, 2004 (13) with permission from Elsevier