Table 2.
Variable | Baseline | PLD | 1-month | 3-month | 6-month |
---|---|---|---|---|---|
TBW (kg) mean ± SD | 123.2 ± 20.4 | 118.2 ± 19.8* | 108.5 ± 18.7* | 100.3 ± 17.1* | 92.9 ± 16.0*† |
EBW (kg) mean ± SD | 55.24 ± 16.94 | 50.25 ± 16.70* | 40.49 ± 15.51* | 32.29 ± 14.05* | 25.79 ± 13.82*† |
BMI (kg/m2) mean ± SD | 45.3 ± 5.9 | 43.5 ± 6.0* | 40.0 ± 5.5* | 36.9 ± 5.1* | 34.4 ± 5.1*† |
Liver volume (cm3) mean ± SD | 2464.6 ± 619.4 | 2148.0 ± 527.2* | 1909.9 ± 433.3* | 1917.0 ± 433.2 (p = 0.775) | 1874.3 ± 387.8 (p = 0.067)† |
PDFF (%) mean ± SD | 16.56 ± 7.78 | 12.71 ± 6.83* | 7.30 ± 4.14* | 4.86 ± 2.94* | 4.37 ± 3.38 (p = 0.007)† |
p-value for baseline comparison with 6-months timepoint provided. TBW total body weight, EBW excess body weight, BMI body mass index, PDFF proton-density fat fraction
p < 0.001 when compared with previous timepoint
p < 0.001 when compared with baseline