Table 4.
Prior to 2007 | 2018 |
---|---|
1st Line | |
Tensilon® | Enlon® |
Pyridostigmine | Pyridostigmine |
Prednisone | Prednisone |
Thymectomy? | Thymectomy! YES |
2nd Line | |
Azathioprine | Azathioprine |
Mycophenolate mofetil | Cyclosporine/tacrolimus |
Cyclosporine | IVIG |
3rd Line | |
IVIG | Plasma exchange |
Plasma exchange | Mycophenolate mofetil Methotrexate |
4th Line | |
None | Eculizumab (Soliris®) Rituximab |
5th Line | |
None | Cyclophosphamide |