Fig 4. SEM estimation using repeated measures analysis with either heterogeneous_CS as in Eq (1), homogeneous_CS in Eq (3), and separate ANOVA analysis approaches at each time point based on the alternative model simulation with ρ = 0.3, n = 12 and a heterogeneous_CS variance covariance structure.

Week 1, Week 7, Week 14, Week 21, and Week 28: SEM distribution for pairwise comparison between treatments at each time point. Proportion = count per bin/1000.