Fig 1. Macroscopic examination of the gastric mucosa of rats obtained from different treated groups.

Control group shows no mucosal ulceration. Ethanol (Positive ulcer) group shows severe hemorrhagic lesions in the mucosa induced by the administration of 7.5ml/kg of absolute ethanol. Groups pre-treated with RK at a dose of 25, 50, 100, and 200 mg/kg or omeprazole (20mg/kg); one hour before absolute ethanol (7.5ml/kg); show marked protection against ethanol-induced gastric ulceration in rats. RK (50 mg/kg)-alone treated group shows no mucosal ulceration.