Table S1.
Hazard ratios (HR) with 95% confidence interval (95% CI) of cancer case fatality according to clinically categories of pre-diagnostic (I) and diagnostic (II) 25-OHD levels
| na | Crude model | Adjusted modelb | |
|---|---|---|---|
| HR (95% CI) | HR (95% CI) | ||
| I. Pre-diagnostic 25-OHDc | |||
| Insufficient [<50 nmol/L] | 142/85 | 1.00 reference | 1.00 reference |
| Sufficient [50–75 nmol/L] | 235/131 | 0.78 (0.59-1.02) | 0.68 (0.52–0.91) |
| Optimal [>75 nmol/L] | 179/97 | 0.74 (0.46–0.91) | 0.59 (0.43–0.81) |
| p for trend | 0.052 | 0.001 | |
| II. Diagnostic 25-OHDc | |||
| Insufficient [<50 nmol/L] | 171/122 | 1.00 reference | 1.00 reference |
| Sufficient [50–75 nmol/L] | 189/96 | 0.47 (0.36–0.61) | 0.51 (0.39–0.67) |
| Optimal [>75 nmol/L] | 196/95 | 0.40 (0.31–0.53) | 0.44 (0.33–0.58) |
| p for trend | <0.001 | <0.001 |
Notes: aNumber of cases/cancer deaths; bAdjusted for sex, age at diagnosis, season of serum sampling, and serum storage time; cThe two serum samples were collected in average 14.4 years apart.