Table S2.
Hazard ratios (HR) with 95% confidence interval (95% CI) of cancer case fatality according to season-standardized 25-OHD levels in predefined categories of pre-diagnostic (I) and diagnostic (II) 25-OHD levels
| na | Crude model | Adjusted modelb | |
|---|---|---|---|
| HR (95% CI) | HR (95% CI) | ||
| I. Pre-diagnostic 25-OHDc | |||
| 1 [<46 nmol/L] | 96/58 | 1.00 reference | 1.00 reference |
| 2 [46–61 nmol/L] | 169/94 | 0.85 (0.61–1.18) | 0.77 (0.56–1.08) |
| 3 [62–81 nmol/L] | 181/100 | 0.74 (0.53–1.02) | 0.63 (0.44–0.91) |
| 4 [≥82 nmol/L] | 110/61 | 0.78 (0.54–1.12) | 0.63 (0.44–0.91) |
| p for trend | 0.113 | 0.007 | |
| II. Diagnostic 25-OHDc | |||
| 1 [<46 nmol/L] | 134/92 | 1.00 reference | 1.00 reference |
| 2 [46–61 nmol/L] | 136/89 | 0.70 (0.52–0.93) | 0.79 (0.59–1.06) |
| 3 [62–81 nmol/L] | 147/69 | 0.42 (0.31–0.57) | 0.47 (0.34–0.64) |
| 4 [≥82 nmol/L] | 139/63 | 0.36 (0.26–0.50) | 0.41 (0.30–0.58) |
| p for trend | <0.001 | <0.001 |
Notes: aNumber of cases/cancer deaths; bAdjusted for sex, age at diagnosis, season of serum sampling, and serum storage time; cThe two serum samples were collected in average 14.4 years apart.