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Palpable purpura in patient with prior psoriasis and psoriatic arthritis at 24 months of ustekinumab therapy (A). Biopsy-confirmed leukocytoclastic vasculitis with perivascular neutrophils, leukocytoclastic debris, and red blood cell extravasation with no vascular immunoglobulin or complement deposition but with full-house granular immune-reactant deposition (IgG, IgM, IgA, C3) at the basement membrane zone (B). (IgG direct immunofluorescence; original magnification, ×100.)
