TABLE II. Summary of plaque reduction neutralisation test (PRNT) titres and selected flavivirus infection enhancement by convalescent dengue virus (DENV)- and Zica virus (ZIKV)-infected samples.
Sample ID | ZIKV | DENV1 | DENV2 | DENV3 | DENV4 | YFV | WNV | ILHV | SLEV | ROCV | |||||||
ZIKV IgG+ | PRNT | PRNT | PRNT | PRNT | PRNT | PRNT | ADE | PRNT | ADE | PRNT | ADE | PRNT | ADE | PRNT | ADE | ||
P01 | 2560 | <20 | <20 | <20 | <20 | <20 | 1.61 | <20 | 2.00 | <20 | 2.33 | <20 | 2.61 | <20 | 3.20 | ||
P05 | 12980 | <20 | <20 | <20 | <20 | 20 | 1.12 | 138 | 1.33 | 20 | 1.81 | <20 | 2.26 | <20 | 1.47 | ||
P11 | 634 | <20 | <20 | <20 | <20 | <20 | 1.19 | <20 | 1.60 | <20 | 1.59 | <20 | 1.50 | <20 | 1.69 | ||
P13 | 1575 | <20 | <20 | <20 | <20 | <20 | 0.67 | 20 | 1.47 | <20 | 3.03 | <20 | 2.78 | <20 | 0.81 | ||
P41 | 343 | <20 | <20 | <20 | <20 | <20 | 1.32 | <20 | 1.82 | <20 | 3.95 | <20 | 4.19 | <20 | 3.53 | ||
P03 | 2560 | <20 | <20 | 320 | 80 | <20 | 1.21 | <20 | 2.36 | <20 | 2.90 | <20 | 3.64 | <20 | 4.65 | ||
P15 | 1280 | <20 | <20 | 80 | 320 | <20 | 1.38 | <20 | 2.36 | 20 | 3.82 | <20 | 3.98 | 20 | 3.84 | ||
P67 | 3729 | 63 | 67 | 340 | 2192 | 20 | 1.09 | 49 | 0.95 | 20 | 1.07 | <20 | 1.44 | 20 | 2.25 | ||
P69 | 536 | <20 | <20 | 570 | 117 | <20 | 0.76 | 20 | 1.03 | <20 | 2.42 | <20 | 2.14 | <20 | 1.90 | ||
P71 | 232 | <20 | <20 | 76 | 215 | <20 | 0.97 | <20 | 0.73 | 20 | 2.97 | 20 | 2.77 | <20 | 2.58 | ||
ZIKV/DENV IgG- | P132 | <20 | 1.75 | <20 | <20 | <20 | <20 | 151 | 1.21 | 20 | 1.54 | 320 | 1.45 | <20 | 1.79 | <20 | 3.89 |
DENV IgG+ | P02 | <20 | 3.31 | <20 | 5120 | <20 | <20 | <20 | 1.30 | <20 | 1.60 | <20 | 1.50 | <20 | 2.10 | <20 | 0.90 |
P322 | 320 | 0.75 | 5120 | <20 | <20 | <20 | 20 | 1.32 | <20 | 2.84 | <20 | 0.91 | <20 | 1.08 | <20 | 2.02 | |
P481 | <20 | 5.38 | 1280 | 5120 | 1280 | <20 | <20 | 1.73 | <20 | 1.90 | <20 | 5.21 | 20 | 4.82 | <20 | 4.06 | |
P491 | <20 | 3.00 | 320 | 40 | >2560 | <20 | 261 | 1.30 | 252 | 2.57 | <20 | 2.03 | <20 | 2.38 | <20 | 2.59 | |
P306 | <20 | 1.75 | 640 | 160 | >2560 | <20 | 1006 | 1.12 | <20 | 1.63 | <20 | 2.02 | <20 | 3.09 | <20 | 4.90 | |
P122 | 320 | 1.00 | 280 | 5120 | 80 | 5120 | 20 | 1.20 | <20 | 1.17 | <20 | 1.21 | <20 | 1.80 | <20 | 1.71 | |
P156 | 5120 | 0.38 | 320 | 320 | 80 | 1280 | <20 | 1.42 | <20 | 1.92 | <20 | 1.16 | 1007 | 1.28 | <20 | 0.06 | |
P234 | 5120 | 0.38 | <20 | 1280 | 1280 | 5120 | <20 | 1.08 | <20 | 0.87 | 1280 | 0.73 | 1280 | 1.91 | <20 | 1.11 |
ADE: antibody dependent enhancement; IgG: immunoglobulin G; ILHV: Ilheus virus; ROCV: Rocio virus; SLEV: Saint Louis encephalitis virus; WNV: West Nile virus; YFV: yellow fever virus.