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. 2019 Aug 8;11:7537–7556. doi: 10.2147/CMAR.S181439

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© 2019 Saavedra et al.

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Serotonin: metabolism and function. L-tryptophan is processed by the tryptophan hydroxylase (TPH^a) and aromatic amino acid decarboxylase (AADC^b) becoming in serotonin. Serotonin is released into bloodstream and distributed to the different organs where participates in the regulation of several functions as temperature, mood, circadian rhythm and appetite control, gut secretion and motility, insulin secretion, adipocyte differentiation and bone mass regulation, platelet aggregation, vascular tone and immune response. More details are provided in the figure.