Figure 7.

Intracellular calcium levels are increased in TrJ Schwann cells. Schwann cells cultured from WT or TrJ-Het mice were loaded with Fura-2AM, and the 340/380 fluorescence intensity ratio was measured and converted to [Ca2+]i using an in vitro calibration curve. Shown are the measurements for individual cells from two separate dissections with the average value ± S.E. (*, p = 0.015, based on a Student's t test).