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. 2019 Jul 22;25:104292. doi: 10.1016/j.dib.2019.104292

Table 2.

All proteins identified in caffeine-exposed EA.hy926 endothelial cells.

Protein name Swiss-Prot ID Gene symbol MS/MS identification score % Cov No. of distinct/total matched peptides pI Intensity (x103 arbitrary unit)
N1 N2 N3 Mean SEM
10 kDa heat shock protein, mitochondrial P61604 HSPE1 44 6.9 1/2 8.9 4330 3885 4178 4131 131
14-3-3 protein beta/alpha P31946 YWHAB 142 12.2 2/5 4.8 20109 24727 21213 22016 1392
14-3-3 protein epsilon P62258 YWHAE 142 13.7 2/5 4.6 5748 5258 5227 5411 169
14-3-3 protein theta P27348 YWHAQ 112 8.2 2/4 4.7 29509 33111 31173 31264 1041
14-3-3 protein zeta/delta P63104 YWHAZ 149 30.6 6/14 4.7 18925 23312 15327 19188 2309
26S protease regulatory subunit 6B P43686 PSMC4 32 6.9 3/3 5.1 43621 52820 44514 46985 2929
26S protease regulatory subunit 7 P35998 PSMC2 43 9 3/4 5.7 13867 19513 13205 15528 2002
26S proteasome non-ATPase regulatory subunit 12 O00232 PSMD12 37 9.6 3/7 7.5 23918 34643 33745 30769 3435
26S proteasome non-ATPase regulatory subunit 14 O00487 PSMD14 44 21.3 2/3 6.1 NA NA NA NA NA
3-ketoacyl-CoA thiolase, mitochondrial P42765 ACAA2 24 6.5 1/1 8.3 NA NA NA NA NA
40S ribosomal protein S11 P62280 RPS11 36 13.3 2/2 10.3 4709 6986 5917 5871 658
40S ribosomal protein S12 P25398 RPS12 109 28 3/6 6.8 18285 10178 13333 13932 2359
40S ribosomal protein S13 P62277 RPS13 129 18.5 3/7 10.5 655 5388 5511 3851 1599
40S ribosomal protein S14 P62263 RPS14 129 21.2 3/5 10.1 30601 36697 31621 32973 1885
40S ribosomal protein S15 P62841 RPS15 74 21.4 2/3 10.4 7814 19633 5966 11138 4281
40S ribosomal protein S16 P62249 RPS16 131 14.4 2/4 10.2 23146 41588 25518 30084 5793
40S ribosomal protein S18 P62269 RPS18 67 18.4 2/3 11.0 5993 6056 7327 6458 435
40S ribosomal protein S19 P39019 RPS19 59 12.4 2/4 10.3 9850 13001 10722 11191 939
40S ribosomal protein S2 P15880 RPS2 128 17.1 3/5 10.3 24603 15691 28391 22895 3764
40S ribosomal protein S20 P60866 RPS20 85 10.1 1/4 10.0 7278 7636 8997 7971 524
40S ribosomal protein S25 P62851 RPS25 78 8 1/3 10.1 2534 3395 7205 4378 1435
40S ribosomal protein S3 P23396 RPS3 69 10.7 3/5 9.7 4920 5693 5855 5489 288
40S ribosomal protein S30 P62861 FAU 46 16.9 1/2 12.2 6266 4765 8417 6483 1060
40S ribosomal protein S3a P61247 RPS3A 47 14.8 3/5 9.8 14393 12075 7992 11487 1871
40S ribosomal protein S4, X isoform P62701 RPS4X 49 25.1 5/7 10.2 9693 8466 7339 8500 680
40S ribosomal protein S5 P46782 RPS5 746 8.8 2/14 9.7 20193 83956 64212 56120 18846
40S ribosomal protein S6 P62753 RPS6 54 12.9 3/4 10.9 3336 7375 9951 6887 1925
40S ribosomal protein S7 P62081 RPS7 97 23.7 4/5 10.1 6560 9532 10157 8749 1110
40S ribosomal protein S8 P62241 RPS8 38 5.3 1/1 10.3 6473 10745 5264 7494 1663
40S ribosomal protein SA P08865 RPSA 110 14.9 2/3 4.8 2129 3513 5312 3651 921
60 kDa heat shock protein, mitochondrial P10809 HSPD1 1040 18.3 7/32 5.7 19242 34047 64047 39112 13180
60S acidic ribosomal protein P0-like Q8NHW5 RPLP0P6 72 18 4/6 5.4 NA NA NA NA NA
60S acidic ribosomal protein P1 P05386 RPLP1 33 14 1/1 4.3 43660 60149 35480 46430 7255
60S acidic ribosomal protein P2 P05387 RPLP2 55 39.1 2/5 4.4 12111 19706 23420 18413 3328
60S ribosomal protein L10 P27635 RPL10 108 12.1 2/3 10.1 6324 13597 77703 32541 22678
60S ribosomal protein L12 P30050 RPL12 114 14.5 2/3 9.5 6275 7716 6677 6889 429
60S ribosomal protein L17 P18621 RPL17 36 14.1 3/5 10.2 8719 6548 9066 8111 788
60S ribosomal protein L18 Q07020 RPL18 43 14.4 2/2 11.7 3933 6316 8707 6319 1378
60S ribosomal protein L19 P84098 RPL19 70 13.3 2/2 11.5 76851 24607 75253 58904 17155
60S ribosomal protein L23 P62829 RPL23 128 14.3 1/3 10.5 5526 7317 10014 7619 1304
60S ribosomal protein L23a P62750 RPL23A 42 13.5 2/2 10.4 8990 17173 14570 13578 2414
60S ribosomal protein L27 P61353 RPL27 39 13.2 2/3 10.6 8472 3960 3332 5255 1619
60S ribosomal protein L29 P47914 RPL29 49 9.4 1/2 11.7 7850 4868 6524 6414 863
60S ribosomal protein L30 P62888 RPL30 93 20 2/3 9.7 10204 31234 11231 17556 6845
60S ribosomal protein L36 Q9Y3U8 RPL36 70 19 2/2 11.6 20307 26460 24430 23732 1810
60S ribosomal protein L38 P63173 RPL38 107 35.7 2/9 10.1 NA NA NA NA NA
60S ribosomal protein L4 P36578 RPL4 35 6.3 2/3 11.1 8221 6733 9680 8212 851
60S ribosomal protein L6 Q02878 RPL6 39 6.3 2/3 10.6 19103 4896 5498 9832 4639
60S ribosomal protein L7 P18124 RPL7 84 14.9 2/4 10.7 NA NA NA NA NA
60S ribosomal protein L7a P62424 RPL7A 27 14.7 3/3 10.6 2578 2984 2804 2788 118
78 kDa glucose-regulated protein P11021 HSPA5 824 32.3 19/39 5.1 NA NA NA NA NA
Acidic leucine-rich nuclear phosphoprotein 32 family member A P39687 ANP32A 102 8.4 1/4 4.0 NA NA NA NA NA
Actin, aortic smooth muscle P62736 ACTA2 2034 26.8 12/198 5.2 NA NA NA NA NA
Activator of 90 kDa heat shock protein ATPase homolog 1 O95433 AHSA1 27 6.5 1/3 5.4 NA NA NA NA NA
Adenylyl cyclase-associated protein 1 Q01518 CAP1 39 11.2 3/8 8.2 NA NA NA NA NA
ADP/ATP translocase 2 P05141 SLC25A5 68 15.8 5/16 9.7 40781 41979 38952 40571 880
ADP-ribosylation factor 1 P84077 ARF1 34 16 2/3 6.3 NA NA NA NA NA
Alpha-actinin-1 P12814 ACTN1 219 9.4 6/9 5.3 NA NA NA NA NA
Alpha-actinin-4 O43707 ACTN4 345 17.2 12/15 5.3 259893 117977 96297 158056 51302
Alpha-enolase P06733 ENO1 1797 46.5 14/215 7.0 160580 195706 188976 181754 10764
Ankyrin repeat domain-containing protein SOWAHA Q2M3V2 SOWAHA 30 4.4 2/97 10.2 83308 87565 65250 78708 6840
Annexin A1 P04083 ANXA1 887 39 10/28 6.6 90580 130768 121496 114281 12149
Annexin A2 P07355 ANXA2 2306 51.9 16/190 7.6 NA NA NA NA NA
Annexin A5 P08758 ANXA5 1474 35.9 11/44 4.9 248633 339406 258133 282057 28805
ATP synthase subunit alpha, mitochondrial P25705 ATP5F1A 296 6.7 2/7 9.2 85448 65941 111158 87515 13094
ATP synthase subunit beta, mitochondrial P06576 ATP5F1B 540 27 10/39 5.3 26094 26613 22905 25204 1159
ATP-dependent RNA helicase DDX1 Q92499 DDX1 99 5.9 2/4 6.8 NA NA NA NA NA
ATP-dependent RNA helicase DDX3X O00571 DDX3X 100 4.8 2/4 6.7 NA NA NA NA NA
Barrier-to-autointegration factor O75531 BANF1 54 27 1/2 5.8 NA NA NA NA NA
Basic leucine zipper and W2 domain-containing protein 1 Q7L1Q6 BZW1 164 7.4 2/5 5.8 NA NA NA NA NA
Beta-actin-like protein 2 Q562R1 ACTBL2 1403 17.8 7/275 5.4 271784 100047 361485 244439 76699
Calnexin P27824 CANX 103 2.5 1/4 4.5 NA NA NA NA NA
Calpain small subunit 1 P04632 CAPNS1 46 9 1/2 5.1 NA NA NA NA NA
Calpain-2 catalytic subunit P17655 CAPN2 30 2.1 1/1 4.9 7615 12113 9347 9692 1310
Calreticulin P27797 CALR 43 12 3/5 4.3 4362 4714 4586 4554 103
Casein kinase II subunit alpha P68400 CSNK2A1 33 4.6 1/2 7.3 NA NA NA NA NA
Cathepsin D P07339 CTSD 156 8.5 2/6 6.1 19350 26988 15663 20667 3335
Caveolin-1 Q03135 CAV1 114 25.3 3/5 5.7 16891 9077 14234 13401 2294
CD59 glycoprotein P13987 CD59 45 9.4 1/3 6.0 6779 15002 11515 11099 2383
Cell division control protein 42 homolog P60953 CDC42 168 19.9 3/10 6.2 22862 38185 24789 28612 4819
Centriolin Q7Z7A1 CNTRL 29 4.1 8/14 5.4 NA NA NA NA NA
Chloride intracellular channel protein 1 O00299 CLIC1 126 14.5 2/4 5.1 35230 32390 31734 33118 1073
Clathrin heavy chain 1 Q00610 CLTC 111 4.7 5/8 5.5 NA NA NA NA NA
Cleavage and polyadenylation specificity factor subunit 6 Q16630 CPSF6 73 8.7 3/3 6.7 NA NA NA NA NA
Coatomer subunit gamma-1 Q9Y678 COPG1 40 2.5 2/2 5.3 NA NA NA NA NA
Cofilin-1 P23528 RPS3 89 15.1 2/3 8.2 17057 11077 11607 13247 1911
Complement component C8 alpha chain P07357 C8A 41 2.9 1/2 6.1 8969 14398 11483 11617 1569
Copine-1 Q99829 CPNE1 112 10.2 4/26 5.5 5980 6341 15281 9201 3042
Core histone macro-H2A.1 O75367 H2AFY 28 8.1 2/2 9.8 NA NA NA NA NA
Cytoskeleton-associated protein 4 Q07065 CKAP4 297 20.1 8/14 5.6 38642 64756 67614 57004 9218
Dehydrogenase/reductase SDR family member 12 A0PJE2 DHRS12 37 2.5 1/1 6.8 NA NA NA NA NA
Dihydropyrimidinase-related protein 1 Q14194 CRMP1 36 10.5 4/5 6.6 36379 2686 34659 24575 10956
DNA damage-binding protein 1 Q16531 DDB1 103 4.6 3/5 5.1 NA NA NA NA NA
DNA replication licensing factor MCM3 P25205 MCM3 46 8.9 5/8 5.5 NA NA NA NA NA
DNA replication licensing factor MCM4 P33991 MCM4 30 5.2 3/5 6.3 NA NA NA NA NA
DNA-(apurinic or apyrimidinic site) lyase P27695 APEX1 39 17.6 3/4 8.3 2478 5382 6307 4722 1153
DNA-dependent protein kinase catalytic subunit P78527 PRKDC 30 3.4 11/25 6.8 NA NA NA NA NA
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 P04843 RPN1 43 4.4 2/3 6.0 39756 47552 45760 44356 2357
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 P04844 RPN2 37 1.9 1/1 5.4 3259 1785 4937 3327 910
E3 ubiquitin/ISG15 ligase TRIM25 Q14258 TRIM25 33 2.9 1/1 8.4 NA NA NA NA NA
EH domain-containing protein 1 Q9H4M9 EHD1 28 4.3 1/1 6.4 2850 2771 2456 2693 120
Elongation factor 1-alpha 1 P68104 EEF1A1 1816 27.1 7/200 9.1 81440 79986 83219 81548 935
Elongation factor 1-delta P29692 EEF1D 60 6.8 2/3 4.9 4253 3855 3494 3868 219
Elongation factor 1-gamma P26641 EEF1G 36 11.9 4/8 6.3 20221 9537 15958 15239 3105
Elongation factor 2 P13639 EEF2 766 26.3 14/41 6.4 154712 236101 219802 203538 24862
Elongation factor Tu, mitochondrial P49411 TUFM 144 19 5/7 7.3 22502 131221 92707 82144 31826
Endoplasmin P14625 HSP90B1 330 10.2 7/19 4.8 NA NA NA NA NA
Enoyl-CoA hydratase, mitochondrial P30084 ECHS1 114 5.9 1/5 8.3 3923 4257 6914 5032 946
Eukaryotic initiation factor 4A-I P60842 EIF4A1 194 17.7 5/9 5.3 4303 13016 11882 9734 2735
Eukaryotic translation initiation factor 3 subunit E P60228 EIF3E 39 4.3 1/1 5.7 NA NA NA NA NA
Eukaryotic translation initiation factor 3 subunit F O00303 EIF3F 89 5.3 1/5 5.2 5340 3388 6309 5012 859
Eukaryotic translation initiation factor 4B P23588 EIF4B 43 2.8 1/2 5.6 NA NA NA NA NA
Ezrin P15311 EZR 292 9.6 6/18 5.9 19984 39956 39871 33270 6643
FACT complex subunit SSRP1 Q08945 SSRP1 29 8.9 4/5 6.5 NA NA NA NA NA
F-actin-capping protein subunit alpha-1 P52907 CAPZA1 42 6.3 1/2 5.5 NA NA NA NA NA
F-actin-capping protein subunit beta P47756 CAPZB 80 9 1/1 5.4 NA NA NA NA NA
Far upstream element-binding protein 2 Q92945 KHSRP 30 1.4 1/1 6.9 2971 3055 4257 3428 415
Fascin Q16658 FSCN1 25 4.9 1/1 6.8 NA NA NA NA NA
Filamin-A P21333 FLNA 499 11.9 19/28 5.7 NA NA NA NA NA
Filamin-B O75369 FLNB 92 2.1 4/6 5.5 41775 44092 39521 41796 1320
Fructose-bisphosphate aldolase A P04075 ALDOA 518 34.9 9/24 8.3 34570 39782 36191 36848 1540
Galectin-1 P09382 LGALS1 380 42.2 5/16 5.3 51517 52333 58343 54064 2152
Gamma-interferon-inducible protein 16 Q16666 IFI16 33 7.4 4/5 9.3 NA NA NA NA NA
Glucose-6-phosphate isomerase P06744 GPI 77 10.2 3/5 8.4 45245 67097 59458 57267 6403
Glucosidase 2 subunit beta P14314 PRKCSH 58 7.8 4/5 4.3 16495 19203 14906 16868 1254
Glutamate dehydrogenase 1, mitochondrial P00367 GLUD1 74 8.2 3/5 7.7 NA NA NA NA NA
Glutathione S-transferase P P09211 GSTP1 303 41.9 4/8 5.4 10233 11386 11396 11005 386
Glyceraldehyde-3-phosphate dehydrogenase P04406 GAPDH 6709 54.9 16/338 8.6 502087 483920 504326 496778 6461
Glycerol kinase 2 Q14410 GK2 40 1.6 1/5 5.6 NA NA NA NA NA
GTP-binding nuclear protein Ran P62826 RAN 82 15.7 3/5 7.0 49761 47473 54665 50633 2121
HEAT repeat-containing protein 5A Q86XA9 HEATR5A 26 1.1 2/134 6.1 83125 92266 68546 81312 6907
Heat shock 70 kDa protein 1A P0DMV8 HSPA1A 224 10.3 5/9 5.5 66770 61785 54021 60859 3709
Heat shock 70 kDa protein 6 P17066 HSPA6 308 9.5 6/12 5.8 64974 60904 59196 61691 1714
Heat shock cognate 71 kDa protein P11142 HSPA8 908 31.6 18/37 5.4 NA NA NA NA NA
Heat shock protein beta-1 P04792 HSPB1 241 37.6 6/12 6.0 43768 32291 27387 34482 4854
Heat shock protein HSP 90-alpha P07900 HSP90AA1 722 28.1 15/40 4.9 243625 290440 265009 266358 13531
Heat shock protein HSP 90-beta P08238 HSP90AB1 774 31.4 17/38 5.0 183622 213245 204446 200438 8783
Heterogeneous nuclear ribonucleoprotein D0 Q14103 HNRNPD 66 14.4 4/6 7.6 3453 6167 6846 5489 1037
Heterogeneous nuclear ribonucleoprotein H P31943 HNRNPH1 254 12.5 4/9 5.9 13440 18911 24674 19008 3243
Heterogeneous nuclear ribonucleoprotein H3 P31942 HNRNPH3 99 4.9 1/3 6.4 4010 3124 4367 3834 370
Heterogeneous nuclear ribonucleoprotein K P61978 HNRNPK 138 11.2 4/7 5.4 18919 15369 21312 18534 1726
Heterogeneous nuclear ribonucleoprotein L P14866 HNRNPL 34 3.1 1/1 8.5 NA NA NA NA NA
Heterogeneous nuclear ribonucleoprotein M P52272 HNRNPM 58 14.8 7/9 8.8 4171 19389 10860 11473 4404
Heterogeneous nuclear ribonucleoprotein Q O60506 SYNCRIP 64 7.1 3/6 8.7 43372 33645 26888 34635 4784
Heterogeneous nuclear ribonucleoprotein R O43390 HNRNPR 91 4.1 2/3 8.2 5230 7021 12551 8268 2203
Heterogeneous nuclear ribonucleoprotein U Q00839 HNRNPU 81 9.8 6/9 5.8 7785 7811 8959 8185 387
Heterogeneous nuclear ribonucleoproteins A2/B1 P22626 HNRNPA2B1 264 14.7 4/8 9.0 9234 7503 13746 10161 1861
Heterogeneous nuclear ribonucleoproteins C1/C2 P07910 HNRNPC 74 5.9 2/3 5.0 NA NA NA NA NA
High mobility group protein HMGI-C P52926 HMGA2 145 33 3/9 10.6 6710 7154 5082 6315 630
Histone H1.4 P10412 HIST1H1E 187 21.5 4/9 11.0 29860 87832 90815 69502 19840
Histone H1.5 P16401 HIST1H1B 38 10.6 2/2 10.9 13058 22109 11606 15591 3286
Histone H2A type 1-B/E P04908 HIST1H2AB 1824 28.5 3/214 11.1 251738 258348 301719 270602 15675
Histone H2A type 1-D P20671 HIST1H2AD 1914 28.5 3/216 10.9 NA NA NA NA NA
Histone H2B type 1-B P33778 HIST1H2BB 7978 34.9 4/395 10.3 NA NA NA NA NA
Histone H2B type 1-C/E/F/G/I P62807 HIST1H2BC 7971 35.7 5/400 10.3 NA NA NA NA NA
Histone H2B type 1-M Q99879 HIST1H2BM 2783 52.4 8/95 10.3 NA NA NA NA NA
Histone H3.1t Q16695 HIST3H3 218 19.1 3/16 11.1 NA NA NA NA NA
Histone H4 P62805 HIST1H4A 1780 51.5 7/88 11.4 350255 303112 359011 337459 17359
Hsc70-interacting protein P50502 ST13 30 5.1 2/2 5.2 3011 2942 1149 2367 609
Importin subunit beta-1 Q14974 KPNB1 30 3.4 2/3 4.7 32953 41673 1683 25436 12140
Importin-9 Q96P70 IPO9 68 3.5 2/6 4.7 NA NA NA NA NA
Integrin beta-4 P16144 ITGB4 44 3.7 6/8 5.7 4247 13505 11076 9609 2771
Interleukin enhancer-binding factor 2 Q12905 ILF2 27 8.7 2/3 5.2 1288 7257 7991 5512 2123
Interleukin enhancer-binding factor 3 Q12906 ILF3 64 7.3 5/5 8.9 2673 3160 3173 3002 164
Kelch-like protein 35 Q6PF15 KLHL35 76 3.9 2/54 8.1 90822 94586 123950 103119 10472
Keratin, type II cytoskeletal 7 P08729 KRT7 456 20.3 9/25 5.4 110541 140404 132067 127671 8896
Keratin, type II cytoskeletal 8 P05787 KRT8 643 33.1 16/34 5.5 168002 180131 185018 177717 5058
l-lactate dehydrogenase A chain P00338 LDHA 384 25.9 8/20 8.4 113122 114854 122830 116936 2989
l-lactate dehydrogenase B chain P07195 LDHB 793 35.3 9/22 5.7 151327 164173 149031 154844 4712
Lysine-specific demethylase 2B Q8NHM5 KDM2B 31 5.2 5/6 8.9 NA NA NA NA NA
Moesin P26038 MSN 765 31.2 17/46 6.1 75143 104685 121996 100608 13678
Myosin light polypeptide 6 P60660 MYL6 145 19.2 2/5 4.6 NA NA NA NA NA
Myosin-9 P35579 MYH9 606 15.1 23/44 5.5 136722 154816 75160 122233 24109
Myristoylated alanine-rich C-kinase substrate P29966 MARCKS 100 11.4 2/3 4.5 NA NA NA NA NA
Nascent polypeptide-associated complex subunit alpha, muscle-specific form E9PAV3 NACA 64 2.5 3/3 9.6 4236 6604 4831 5224 711
Neurobeachin-like protein 2 Q6ZNJ1 NBEAL2 26 0.9 3/5 6.0 NA NA NA NA NA
Neuroblast differentiation-associated protein AHNAK Q09666 AHNAK 106 3.9 14/28 5.8 31540 28337 24712 28197 1972
Nuclear autoantigenic sperm protein P49321 NASP 74 2.9 1/2 4.3 NA NA NA NA NA
Nucleolin P19338 NCL 340 12.4 5/14 4.6 18999 29968 26172 25046 3216
Nucleophosmin P06748 NPM1 560 25.5 6/22 4.6 70290 87003 71940 76411 5317
Nucleoside diphosphate kinase A P15531 NME1 256 28.9 3/9 5.8 NA NA NA NA NA
Nucleoside diphosphate kinase B P22392 NME2 110 23.7 2/5 8.5 NA NA NA NA NA
Nucleosome assembly protein 1-like 1 P55209 NAP1L1 244 11.8 3/9 4.4 14361 22476 19359 18732 2363
Obg-like ATPase 1 Q9NTK5 OLA1 65 7.6 2/3 7.6 11814 7151 3737 7567 2341
Parathymosin P20962 PTMS 42 11.8 1/1 4.1 NA NA NA NA NA
Peptidyl-prolyl cis-trans isomerase A P62937 PPIA 855 58.2 8/44 7.7 231705 300387 236591 256227 22125
Peptidyl-prolyl cis-trans isomerase B P23284 PPIB 175 28.2 5/8 9.4 12703 18919 14342 15322 1860
Peroxiredoxin-1 Q06830 PRDX1 206 48.7 8/15 8.3 27647 30113 35543 31101 2332
Peroxiredoxin-6 P30041 PRDX6 54 22.3 3/6 6.0 1613 1696 2904 2071 417
Phenylalanine--tRNA ligase alpha subunit Q9Y285 FARSA 31 7.5 3/4 7.3 11640 18021 14123 14595 1857
Phosphoglycerate kinase 1 P00558 PGK1 468 30.9 9/19 8.3 35780 29231 26549 30520 2741
Phosphoglycerate mutase 1 P18669 PGAM1 154 22 3/7 6.7 NA NA NA NA NA
Plasminogen activator inhibitor 2 P05120 SERPINB2 40 6.7 2/3 5.5 10671 46264 15720 24218 11119
Plectin Q15149 PLEC 629 10.1 40/76 5.7 129537 94526 112414 112159 10108
Poly(rC)-binding protein 2 Q15366 PCBP2 143 10.4 3/5 6.3 NA NA NA NA NA
Polymerase I and transcript release factor Q6NZI2 CAVIN1 203 7.7 2/4 5.5 18569 26062 26052 23561 2496
Polypyrimidine tract-binding protein 1 P26599 PTBP1 77 8.1 2/3 9.2 NA NA NA NA NA
PRA1 family protein 3 O75915 ARL6IP5 75 10.1 1/2 9.8 NA NA NA NA NA
Prelamin-A/C P02545 LMNA 801 30.4 18/42 6.6 178301 195963 179349 184538 5721
Probable ATP-dependent RNA helicase DDX17 Q92841 DDX17 70 7.8 6/11 8.5 10037 3635 7211 6961 1852
Probable ATP-dependent RNA helicase DDX5 P17844 DDX5 160 9.1 4/6 9.1 60887 75245 68979 68370 4156
Profilin-1 P07737 PFN1 173 29.3 4/11 8.4 25682 31776 35538 30999 2871
Prohibitin P35232 PHB 60 3.7 1/3 5.6 3563 3755 3652 3657 56
Prohibitin-2 Q99623 PHB2 84 6 2/3 9.8 3060 11607 4513 6393 2640
Proliferating cell nuclear antigen P12004 PCNA 89 18.8 3/5 4.6 10521 15864 15787 14057 1768
Proliferation-associated protein 2G4 Q9UQ80 PA2G4 60 13.5 4/5 6.1 15606 4851 5579 8679 3470
Proteasome activator complex subunit 2 Q9UL46 PSME2 84 5.4 1/3 5.5 1510 6784 13337 7211 3421
Protein disulfide-isomerase A3 P30101 PDIA3 198 13.5 5/9 6.0 14479 24142 14370 17664 3239
Protein disulfide-isomerase A4 P13667 PDIA4 60 1.9 1/2 5.0 1248 3013 3897 2719 779
Protein disulfide-isomerase A6 Q15084 PDIA6 103 16.4 4/7 5.0 15804 36195 31234 27744 6139
Protein MCM10 homolog Q7L590 MCM10 20 2.6 2/16 9.0 NA NA NA NA NA
Protein S100-A10 P60903 S100A10 152 35.1 2/6 6.8 5636 5348 5490 5491 83
Protein S100-A11 P31949 S100A11 973 34.3 3/43 6.6 26304 94980 30001 50428 22301
Protein S100-A6 P06703 S100A6 63 8.9 1/2 5.3 7360 7574 5655 6863 607
Protein-glutamine gamma-glutamyltransferase 2 P21980 TGM2 320 16.4 8/13 5.1 34271 36100 28001 32791 2452
Prothymosin alpha P06454 PTMA 87 12.6 2/2 3.7 1708 2465 1973 2049 222
Proto-oncogene serine/threonine-protein kinase mos P00540 MOS 51 2.6 1/15 9.2 118112 86458 107713 104095 9315
Purine nucleoside phosphorylase P00491 PNP 47 12.1 2/4 6.5 4157 6685 5275 5372 731
Putative Ras-related protein Rab-1C Q92928 RAB1C 39 28.9 3/4 5.3 1518 2153 1326 1666 250
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial P11177 PDHB 55 8.9 2/3 6.2 31990 32117 37655 33921 1868
Pyruvate kinase PKM P14618 PKM 2280 55.9 23/173 8.0 397067 567868 467824 477586 49547
Rab GDP dissociation inhibitor beta P50395 GDI2 139 5.6 3/8 6.1 4013 6661 13713 8129 2895
Ras GTPase-activating-like protein IQGAP1 P46940 IQGAP1 56 3.7 4/7 6.1 8004 6786 7340 7376 352
Receptor of activated protein C kinase 1 P63244 RACK1 42 15.5 4/5 7.6 1002 3333 1849 2061 681
Rho GDP-dissociation inhibitor 1 P52565 ARHGDIA 100 7.4 1/2 5.0 4867 3912 1651 3477 954
Rho GDP-dissociation inhibitor 2 P52566 ARHGDIB 48 12.9 1/1 5.1 NA NA NA NA NA
Rho GTPase-activating protein 26 Q9UNA1 ARHGAP26 25 2.9 2/17 6.2 NA NA NA NA NA
Ribosome-binding protein 1 Q9P2E9 RRBP1 40 1.9 2/3 8.7 NA NA NA NA NA
RNA polymerase II-associated protein 1 Q9BWH6 RPAP1 32 0.7 1/3 6.0 3437 6928 9264 6543 1693
RNA-binding protein FUS P35637 FUS 231 8.9 3/4 9.4 NA NA NA NA NA
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit P36873 PPP1CC 45 9.9 2/3 6.1 2873 5623 3209 3902 866
Serpin H1 P50454 SERPINH1 125 8.9 2/4 8.8 40068 47929 46178 44725 2383
Signal recognition particle 14 kDa protein P37108 SRP14 100 10.3 1/1 10.1 NA NA NA NA NA
Small nuclear ribonucleoprotein Sm D1 P62314 SNRPD1 138 16.8 1/6 11.6 6398 47268 45270 32978 13303
Splicing factor, proline- and glutamine-rich P23246 SFPQ 94 7.5 4/10 9.5 11573 10818 13601 11998 831
Stathmin P16949 STMN1 54 15.4 2/6 5.8 47794 7520 23965 26426 11691
Stress-70 protein, mitochondrial P38646 HSPA9 47 8.7 5/6 5.9 13151 19381 11846 14792 2325
Stress-induced-phosphoprotein 1 P31948 STIP1 45 15.5 6/12 6.4 4714 8504 9411 7543 1439
Sulfotransferase 1A3 P0DMM9 SULT1A3 74 11.2 2/4 5.7 NA NA NA NA NA
Surfeit locus protein 4 O15260 SURF4 76 6.7 1/4 7.6 NA NA NA NA NA
T-complex protein 1 subunit alpha P17987 TCP1 45 9.9 4/6 5.8 4850 10421 13921 9731 2641
T-complex protein 1 subunit delta P50991 CCT4 149 4.8 2/3 8.0 2671 2174 1872 2239 233
T-complex protein 1 subunit eta Q99832 CCT7 234 4.6 1/9 7.6 NA NA NA NA NA
T-complex protein 1 subunit gamma P49368 CCT3 41 4.8 1/1 6.1 NA NA NA NA NA
T-complex protein 1 subunit theta P50990 CCT8 109 7.5 3/5 5.4 7786 8308 9644 8579 553
T-complex protein 1 subunit zeta P40227 CCT6A 97 15.6 5/7 6.2 19661 26392 26299 24117 2228
Thioredoxin domain-containing protein 5 Q8NBS9 TXNDC5 177 15 5/9 5.6 5551 38511 4363 16142 11190
Transaldolase P37837 TALDO1 41 3.3 1/4 6.4 15741 13947 8625 12771 2137
Transcription elongation factor A protein-like 3 Q969E4 TCEAL3 31 24 3/5 4.9 NA NA NA NA NA
Transcription factor BTF3 P20290 BTF3 62 10.7 1/2 9.4 NA NA NA NA NA
Transgelin-2 P37802 TAGLN2 732 49.7 7/28 8.4 57399 110480 76795 81558 15507
Transitional endoplasmic reticulum ATPase P55072 VCP 161 6.8 4/12 5.1 6374 29473 14137 16661 6787
Transketolase P29401 TKT 643 11.4 6/16 7.6 24076 47350 44148 38524 7283
Triosephosphate isomerase P60174 TPI1 643 35.7 7/22 5.7 146216 151248 177844 158436 9812
Tropomyosin alpha-1 chain P09493 TPM1 132 14.1 3/8 4.7 NA NA NA NA NA
Tropomyosin alpha-3 chain P06753 TPM3 167 9.5 2/6 4.7 11546 13209 13043 12599 529
Tubulin alpha-1A chain Q71U36 TUBA1A 688 31.5 10/34 4.9 NA NA NA NA NA
Tubulin alpha-1B chain P68363 TUBA1B 708 28.4 9/34 4.9 256115 272977 268453 265848 5039
Tubulin beta chain P07437 TUBB 887 32.7 11/35 4.8 146362 176721 141763 154949 10967
Tubulin beta-4A chain P04350 TUBB4A 396 32.2 9/17 4.8 121377 132544 105460 119794 7859
Tubulin beta-4B chain P68371 TUBB4B 810 32.6 11/33 4.8 NA NA NA NA NA
Tubulin beta-6 chain Q9BUF5 TUBB6 189 18.8 6/12 4.8 77941 88821 57231 74664 9265
Ubiquitin carboxyl-terminal hydrolase isozyme L1 P09936 UCHL1 80 15.2 2/4 5.3 18181 17649 41400 25743 7830
Ubiquitin-40S ribosomal protein S27a P62979 RPS27A 377 19.9 3/10 9.7 NA NA NA NA NA
Ubiquitin-like modifier-activating enzyme 1 P22314 UBA1 335 10.7 7/12 5.5 100384 139631 136812 125609 12639
UPF0183 protein C16orf70 Q9BSU1 C16orf70 31 3.6 1/6 7.6 44961 24989 45433 38461 6738
UPF0258 protein KIAA1024 Q9UPX6 KIAA1024 38 7.2 5/8 7.0 5248 8423 6191 6621 941
Vimentin P08670 VIM 3540 55.2 28/248 5.1 912676 1042672 935577 963641 40064
Vinculin P18206 VCL 157 6.4 5/11 5.5 23215 25731 31166 26704 2346
X-ray repair cross-complementing protein 6 P12956 XRCC6 195 16.4 6/9 6.2 7446 3195 21075 10572 5393
Zyxin Q15942 ZYX 35 2.6 1/1 6.2 4116 1800 1654 2523 797

%Cov = %Sequence coverage = (number of the matched residues/total number of residues in the entire sequence) x 100%.

NA = not applicable (protein was identified in the sample but its MS/MS spectra did not meet predefined criteria for high-confident intensity analysis).