Table 3.
All proteins identified in EGCG-exposed EA.hy926 endothelial cells.
| Protein name | Swiss-Prot ID | Gene symbol | MS/MS identification score | % Cov | No. of distinct/total matched peptides | pI | Intensity (x103 arbitrary unit) |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N1 | N2 | N3 | Mean | SEM | |||||||
| 14-3-3 protein beta/alpha | P31946 | YWHAB | 142 | 12.2 | 2/7 | 4.8 | 14856 | 25768 | 24104 | 21576 | 3394 |
| 14-3-3 protein epsilon | P62258 | YWHAE | 126 | 24.3 | 4/6 | 4.6 | 9737 | 11989 | 6523 | 9416 | 1586 |
| 14-3-3 protein theta | P27348 | YWHAQ | 75 | 15.5 | 4/4 | 4.7 | 35166 | 33504 | 30882 | 33184 | 1247 |
| 14-3-3 protein zeta/delta | P63104 | YWHAZ | 150 | 45.3 | 9/20 | 4.7 | 23094 | 28757 | 41849 | 31234 | 5554 |
| 26S protease regulatory subunit 6A | P17980 | PSMC3 | 88 | 11.4 | 3/5 | 5.1 | 17797 | 51266 | 42507 | 37190 | 10021 |
| 26S protease regulatory subunit 6B | P43686 | PSMC4 | 47 | 5.3 | 3/5 | 5.1 | 94361 | 84996 | 70360 | 83239 | 6984 |
| 26S protease regulatory subunit 7 | P35998 | PSMC2 | 79 | 5.8 | 2/4 | 5.7 | 17425 | 17155 | 14886 | 16489 | 805 |
| 26S proteasome non-ATPase regulatory subunit 12 | O00232 | PSMD12 | 27 | 8.3 | 3/9 | 7.5 | 32563 | 32999 | 27461 | 31007 | 1778 |
| 40S ribosomal protein S11 | P62280 | RPS11 | 61 | 7 | 1/2 | 10.3 | 2520 | 4150 | 5421 | 4030 | 839 |
| 40S ribosomal protein S12 | P25398 | RPS12 | 86 | 34.1 | 4/7 | 6.8 | 109186 | 7943 | 7527 | 41552 | 33817 |
| 40S ribosomal protein S13 | P62277 | RPS13 | 150 | 17.9 | 2/8 | 10.5 | 10185 | 8264 | 7963 | 8804 | 696 |
| 40S ribosomal protein S14 | P62263 | RPS14 | 103 | 7.3 | 1/2 | 10.1 | 18814 | 9167 | 2434 | 10138 | 4753 |
| 40S ribosomal protein S15 | P62841 | RPS15 | 94 | 13.1 | 1/3 | 10.4 | 16183 | 18812 | 4042 | 13012 | 4549 |
| 40S ribosomal protein S16 | P62249 | RPS16 | 177 | 21.9 | 3/6 | 10.2 | 34980 | 27926 | 27421 | 30109 | 2440 |
| 40S ribosomal protein S18 | P62269 | RPS18 | 47 | 5.3 | 1/2 | 11.0 | 5469 | 3885 | 10012 | 6455 | 1836 |
| 40S ribosomal protein S19 | P39019 | RPS19 | 77 | 25.5 | 4/4 | 10.3 | 41636 | 62034 | 41193 | 48288 | 6874 |
| 40S ribosomal protein S2 | P15880 | RPS2 | 84 | 19.5 | 4/6 | 10.3 | 70528 | 78705 | 69344 | 72859 | 2943 |
| 40S ribosomal protein S20 | P60866 | RPS20 | 60 | 10.1 | 1/4 | 10.0 | 12786 | 10273 | 18891 | 13983 | 2559 |
| 40S ribosomal protein S24 | P62847 | RPS24 | 34 | 11.3 | 1/3 | 10.8 | 4519 | 2670 | 1627 | 2939 | 846 |
| 40S ribosomal protein S25 | P62851 | RPS25 | 85 | 8 | 1/2 | 10.1 | 6522 | 2931 | 7305 | 5586 | 1347 |
| 40S ribosomal protein S3 | P23396 | RPS3 | 49 | 10.7 | 2/3 | 9.7 | 4583 | 6576 | 5298 | 5485 | 583 |
| 40S ribosomal protein S30 | P62861 | FAU | 49 | 16.9 | 1/2 | 12.2 | 9426 | 6156 | 10466 | 8683 | 1299 |
| 40S ribosomal protein S3a | P61247 | RPS3A | 66 | 11 | 3/6 | 9.8 | 8707 | 7249 | 5894 | 7283 | 812 |
| 40S ribosomal protein S5 | P46782 | RPS5 | 717 | 7.4 | 1/12 | 9.7 | 99724 | 82871 | 71606 | 84734 | 8170 |
| 40S ribosomal protein S7 | P62081 | RPS7 | 114 | 26.8 | 5/9 | 10.1 | 4548 | 11324 | 9732 | 8535 | 2045 |
| 40S ribosomal protein S8 | P62241 | RPS8 | 62 | 10.6 | 2/4 | 10.3 | 4813 | 6137 | 7097 | 6016 | 662 |
| 40S ribosomal protein SA | P08865 | RPSA | 111 | 9.5 | 2/4 | 4.8 | 11151 | 8777 | 13306 | 11078 | 1308 |
| 60 kDa heat shock protein, mitochondrial | P10809 | HSPD1 | 869 | 19.2 | 9/30 | 5.7 | 82898 | 58620 | 65020 | 68846 | 7265 |
| 60S acidic ribosomal protein P0-like | Q8NHW5 | RPLP0P6 | 78 | 17.7 | 4/5 | 5.4 | NA | NA | NA | NA | NA |
| 60S acidic ribosomal protein P1 | P05386 | RPLP1 | 39 | 14 | 1/2 | 4.3 | 53323 | 21160 | 38947 | 37810 | 9302 |
| 60S acidic ribosomal protein P2 | P05387 | RPLP2 | 66 | 39.1 | 2/3 | 4.4 | 9083 | 20753 | 6118 | 11985 | 4467 |
| 60S ribosomal protein L10 | P27635 | RPL10 | 111 | 6.5 | 1/3 | 10.1 | 864 | 1808 | 7593 | 3422 | 2104 |
| 60S ribosomal protein L12 | P30050 | RPL12 | 131 | 28.5 | 3/5 | 9.5 | 9704 | 14112 | 7536 | 10451 | 1935 |
| 60S ribosomal protein L15 | P61313 | RPL15 | 39 | 4.4 | 1/1 | 11.6 | 6040 | 1241 | 5128 | 4137 | 1471 |
| 60S ribosomal protein L18 | Q07020 | RPL18 | 98 | 6.9 | 1/4 | 11.7 | 7596 | 8074 | 5352 | 7007 | 839 |
| 60S ribosomal protein L19 | P84098 | RPL19 | 62 | 4.6 | 1/2 | 11.5 | 22554 | 1900 | 21706 | 15387 | 6748 |
| 60S ribosomal protein L23 | P62829 | RPL23 | 95 | 14.3 | 1/2 | 10.5 | 2755 | 6535 | 10270 | 6520 | 2169 |
| 60S ribosomal protein L27 | P61353 | RPL27 | 35 | 6.6 | 1/1 | 10.6 | 2976 | 9151 | 4588 | 5572 | 1849 |
| 60S ribosomal protein L27a | P46776 | RPL27A | 49 | 11.5 | 2/4 | 11.0 | 26212 | 27037 | 17693 | 23647 | 2987 |
| 60S ribosomal protein L29 | P47914 | RPL29 | 77 | 9.4 | 1/2 | 11.7 | 5297 | 4889 | 8918 | 6368 | 1280 |
| 60S ribosomal protein L30 | P62888 | RPL30 | 95 | 13.9 | 1/2 | 9.7 | 27044 | 23235 | 8346 | 19542 | 5705 |
| 60S ribosomal protein L36 | Q9Y3U8 | RPL36 | 41 | 8.6 | 1/1 | 11.6 | 5046 | 3454 | 2748 | 3749 | 680 |
| 60S ribosomal protein L38 | P63173 | RPL38 | 92 | 35.7 | 2/8 | 10.1 | NA | NA | NA | NA | NA |
| 60S ribosomal protein L4 | P36578 | RPL4 | 43 | 2.8 | 1/1 | 11.1 | 10869 | 10149 | 5538 | 8852 | 1670 |
| 60S ribosomal protein L6 | Q02878 | RPL6 | 54 | 6.3 | 2/4 | 10.6 | 14176 | 6382 | 3399 | 7986 | 3213 |
| 60S ribosomal protein L7 | P18124 | RPL7 | 104 | 17.3 | 4/5 | 10.7 | 11702 | 7014 | 6816 | 8511 | 1597 |
| 60S ribosomal protein L7a | P62424 | RPL7A | 71 | 17.7 | 5/7 | 10.6 | 14133 | 9188 | 7774 | 10365 | 1928 |
| 78 kDa glucose-regulated protein | P11021 | HSPA5 | 1086 | 27.8 | 16/40 | 5.1 | NA | NA | NA | NA | NA |
| Acidic leucine-rich nuclear phosphoprotein 32 family member A | P39687 | ANP32A | 68 | 8.4 | 1/4 | 4.0 | NA | NA | NA | NA | NA |
| Actin, aortic smooth muscle | P62736 | ACTA2 | 1823 | 23.1 | 9/163 | 5.2 | NA | NA | NA | NA | NA |
| Activator of 90 kDa heat shock protein ATPase homolog 1 | O95433 | AHSA1 | 96 | 21.6 | 4/5 | 5.4 | NA | NA | NA | NA | NA |
| ADP/ATP translocase 2 | P05141 | SLC25A5 | 64 | 13.1 | 4/7 | 9.7 | 46370 | 18671 | 43459 | 36167 | 8788 |
| ADP-ribosylation factor 1 | P84077 | ARF1 | 30 | 9.9 | 1/2 | 6.3 | NA | NA | NA | NA | NA |
| Alpha-actinin-1 | P12814 | ACTN1 | 149 | 9.9 | 8/13 | 5.3 | NA | NA | NA | NA | NA |
| Alpha-actinin-4 | O43707 | ACTN4 | 272 | 13.4 | 8/11 | 5.3 | 90204 | 96621 | 81692 | 89506 | 4324 |
| Alpha-enolase | P06733 | ENO1 | 1868 | 45.2 | 13/419 | 7.0 | 202358 | 212994 | 130496 | 181949 | 25909 |
| Annexin A1 | P04083 | ANXA1 | 1066 | 45.1 | 12/35 | 6.6 | 148786 | 110784 | 108081 | 122551 | 13141 |
| Annexin A2 | P07355 | ANXA2 | 1653 | 59.3 | 19/73 | 7.6 | NA | NA | NA | NA | NA |
| Annexin A5 | P08758 | ANXA5 | 1475 | 41.3 | 13/44 | 4.9 | 475467 | 433887 | 276964 | 395440 | 60441 |
| ATP synthase subunit alpha, mitochondrial | P25705 | ATP5F1A | 310 | 5.8 | 2/6 | 9.2 | 83468 | 99810 | 108357 | 97211 | 7302 |
| ATP synthase subunit beta, mitochondrial | P06576 | ATP5F1B | 429 | 27 | 10/21 | 5.3 | 48637 | 37303 | 23580 | 36507 | 7244 |
| ATP-dependent RNA helicase A | Q08211 | DHX9 | 32 | 3.5 | 4/9 | 6.4 | 1931 | 4245 | 3151 | 3109 | 668 |
| ATP-dependent RNA helicase DDX3X | O00571 | DDX3X | 48 | 7.4 | 3/6 | 6.7 | NA | NA | NA | NA | NA |
| Barrier-to-autointegration factor | O75531 | BANF1 | 67 | 27 | 1/2 | 5.8 | NA | NA | NA | NA | NA |
| Basic leucine zipper and W2 domain-containing protein 1 | Q7L1Q6 | BZW1 | 171 | 8.6 | 3/4 | 5.8 | NA | NA | NA | NA | NA |
| Beta-actin-like protein 2 | Q562R1 | ACTBL2 | 1238 | 17.6 | 6/237 | 5.4 | 352799 | 135984 | 323943 | 270909 | 67975 |
| Beta-enolase | P13929 | ENO3 | 564 | 21.7 | 5/80 | 7.6 | NA | NA | NA | NA | NA |
| Calnexin | P27824 | CANX | 130 | 7.1 | 3/5 | 4.5 | NA | NA | NA | NA | NA |
| Calpain small subunit 1 | P04632 | CAPNS1 | 50 | 9 | 1/2 | 5.1 | NA | NA | NA | NA | NA |
| Calreticulin | P27797 | CALR | 96 | 12 | 3/6 | 4.3 | 2845 | 5237 | 8126 | 5403 | 1527 |
| Cathepsin D | P07339 | CTSD | 86 | 10.7 | 3/6 | 6.1 | 33499 | 28185 | 24919 | 28867 | 2500 |
| Caveolin-1 | Q03135 | CAV1 | 87 | 13.5 | 2/3 | 5.7 | NA | NA | NA | NA | NA |
| CD59 glycoprotein | P13987 | CD59 | 28 | 9.4 | 1/1 | 6.0 | NA | NA | NA | NA | NA |
| Centriolin | Q7Z7A1 | CNTRL | 30 | 2.8 | 7/13 | 5.4 | 10908 | 14867 | 3245 | 9673 | 3411 |
| Chloride intracellular channel protein 1 | O00299 | CLIC1 | 152 | 12.4 | 2/3 | 5.1 | 30494 | 32869 | 20242 | 27868 | 3874 |
| Chloride intracellular channel protein 4 | Q9Y696 | CLIC4 | 50 | 16.6 | 3/6 | 5.5 | NA | NA | NA | NA | NA |
| Clathrin heavy chain 1 | Q00610 | CLTC | 114 | 4.5 | 5/9 | 5.5 | NA | NA | NA | NA | NA |
| Coatomer subunit gamma-1 | Q9Y678 | COPG1 | 64 | 3.7 | 2/2 | 5.3 | NA | NA | NA | NA | NA |
| Cofilin-1 | P23528 | RPS3 | 78 | 6.6 | 1/2 | 8.2 | 20964 | 16535 | 14004 | 17168 | 2034 |
| Cofilin-2 | Q9Y281 | CFL2 | 70 | 11.4 | 2/3 | 7.7 | NA | NA | NA | NA | NA |
| Copine-1 | Q99829 | CPNE1 | 136 | 10.2 | 4/31 | 5.5 | 12777 | 9149 | 13899 | 11941 | 1433 |
| CREB-binding protein | Q92793 | CREBBP | 30 | 0.5 | 1/2 | 8.8 | 3965 | 3520 | 7964 | 5150 | 1413 |
| Cysteine and glycine-rich protein 1 | P21291 | CSRP1 | 40 | 8.8 | 1/2 | 8.9 | NA | NA | NA | NA | NA |
| Cytoplasmic dynein 1 heavy chain 1 | Q14204 | DYNC1H1 | 31 | 2.8 | 10/12 | 6.0 | NA | NA | NA | NA | NA |
| Cytoskeleton-associated protein 4 | Q07065 | CKAP4 | 328 | 25.7 | 11/19 | 5.6 | 56769 | 66405 | 59821 | 60998 | 2843 |
| Dedicator of cytokinesis protein 10 | Q96BY6 | DOCK10 | 29 | 2 | 4/10 | 6.7 | 28536 | 33353 | 18905 | 26932 | 4247 |
| Dehydrogenase/reductase SDR family member 12 | A0PJE2 | DHRS12 | 38 | 2.5 | 1/1 | 6.8 | NA | NA | NA | NA | NA |
| DNA damage-binding protein 1 | Q16531 | DDB1 | 136 | 3.4 | 3/5 | 5.1 | NA | NA | NA | NA | NA |
| DNA-(apurinic or apyrimidinic site) lyase | P27695 | APEX1 | 54 | 5.3 | 1/2 | 8.3 | 6105 | 4535 | 4671 | 5104 | 502 |
| EH domain-containing protein 1 | Q9H4M9 | EHD1 | 42 | 7.9 | 2/2 | 6.4 | 4883 | 3519 | 3475 | 3959 | 462 |
| Elongation factor 1-alpha 1 | P68104 | EEF1A1 | 1873 | 27.1 | 7/337 | 9.1 | 61754 | 77139 | 66647 | 68513 | 4538 |
| Elongation factor 1-delta | P29692 | EEF1D | 118 | 16.7 | 4/6 | 4.9 | 5820 | 6117 | 4248 | 5395 | 580 |
| Elongation factor 1-gamma | P26641 | EEF1G | 40 | 9.2 | 5/7 | 6.3 | 21454 | 8287 | 8522 | 12755 | 4350 |
| Elongation factor 2 | P13639 | EEF2 | 782 | 24.4 | 13/34 | 6.4 | 273816 | 181870 | 119469 | 191719 | 44827 |
| Elongation factor Tu, mitochondrial | P49411 | TUFM | 104 | 15.3 | 4/6 | 7.3 | 100052 | 121532 | 94084 | 105223 | 8335 |
| Endoplasmin | P14625 | HSP90B1 | 384 | 10.5 | 7/17 | 4.8 | NA | NA | NA | NA | NA |
| Enoyl-CoA hydratase, mitochondrial | P30084 | ECHS1 | 126 | 5.9 | 1/2 | 8.3 | 19025 | 6669 | 4936 | 10210 | 4436 |
| Eukaryotic initiation factor 4A-I | P60842 | EIF4A1 | 186 | 8.6 | 3/7 | 5.3 | 15563 | 6869 | 21492 | 14641 | 4246 |
| Eukaryotic translation initiation factor 3 subunit E | P60228 | EIF3E | 76 | 4.3 | 1/2 | 5.7 | NA | NA | NA | NA | NA |
| Eukaryotic translation initiation factor 3 subunit H | O15372 | EIF3H | 31 | 5.4 | 1/1 | 6.1 | 986 | 3977 | 1907 | 2290 | 884 |
| Eukaryotic translation initiation factor 4B | P23588 | EIF4B | 53 | 2.8 | 1/2 | 5.6 | NA | NA | NA | NA | NA |
| Eukaryotic translation initiation factor 5A-1 | P63241 | EIF5A | 59 | 5.2 | 1/1 | 5.1 | 5721 | 3751 | 4992 | 4821 | 575 |
| Exportin-2 | P55060 | CSE1L | 39 | 3.5 | 3/239 | 5.5 | 162139 | 124377 | 170237 | 152251 | 14132 |
| Ezrin | P15311 | EZR | 293 | 12.1 | 8/16 | 5.9 | 18275 | 28096 | 44421 | 30264 | 7625 |
| FACT complex subunit SSRP1 | Q08945 | SSRP1 | 65 | 6.5 | 3/7 | 6.5 | NA | NA | NA | NA | NA |
| F-actin-capping protein subunit alpha-1 | P52907 | CAPZA1 | 47 | 6.3 | 1/2 | 5.5 | NA | NA | NA | NA | NA |
| F-actin-capping protein subunit beta | P47756 | CAPZB | 49 | 18.4 | 3/6 | 5.4 | NA | NA | NA | NA | NA |
| Fascin | Q16658 | FSCN1 | 44 | 8.5 | 3/3 | 6.8 | NA | NA | NA | NA | NA |
| F-box/LRR-repeat protein 19 | Q6PCT2 | FBXL19 | 30 | 2 | 2/3 | 9.4 | 13989 | 14989 | 6940 | 11973 | 2533 |
| Filamin-A | P21333 | FLNA | 534 | 12.6 | 21/38 | 5.7 | 125578 | 212121 | 129322 | 155673 | 28244 |
| Filamin-B | O75369 | FLNB | 129 | 5.5 | 10/14 | 5.5 | 46259 | 120035 | 47982 | 71425 | 24310 |
| Fructose-bisphosphate aldolase A | P04075 | ALDOA | 477 | 34.9 | 10/24 | 8.3 | 55206 | 76813 | 42632 | 58217 | 9981 |
| Fructose-bisphosphate aldolase C | P09972 | ALDOC | 35 | 6.3 | 1/1 | 6.4 | 5871 | 3760 | 2508 | 4046 | 981 |
| Galectin-1 | P09382 | LGALS1 | 376 | 40.7 | 5/14 | 5.3 | 53517 | 62833 | 55917 | 57422 | 2793 |
| Glucose-6-phosphate isomerase | P06744 | GPI | 120 | 7.2 | 2/5 | 8.4 | 115873 | 121211 | 95298 | 110794 | 7900 |
| Glucosidase 2 subunit beta | P14314 | PRKCSH | 70 | 8 | 4/6 | 4.3 | 41191 | 66489 | 26569 | 44750 | 11660 |
| Glutathione S-transferase P | P09211 | GSTP1 | 310 | 41.9 | 4/12 | 5.4 | 12223 | 11704 | 11259 | 11729 | 278 |
| Glyceraldehyde-3-phosphate dehydrogenase | P04406 | GAPDH | 6498 | 54.6 | 14/564 | 8.6 | 566470 | 555632 | 527936 | 550012 | 11473 |
| Glycerol kinase 2 | Q14410 | GK2 | 49 | 1.6 | 1/4 | 5.6 | NA | NA | NA | NA | NA |
| GTP-binding nuclear protein Ran | P62826 | RAN | 121 | 15.7 | 3/6 | 7.0 | 52227 | 53052 | 55041 | 53440 | 835 |
| Heat shock 70 kDa protein 6 | P17066 | HSPA6 | 335 | 8.9 | 5/10 | 5.8 | 77096 | 77483 | 54634 | 69738 | 7553 |
| Heat shock cognate 71 kDa protein | P11142 | HSPA8 | 946 | 26.2 | 16/40 | 5.4 | NA | NA | NA | NA | NA |
| Heat shock protein beta-1 | P04792 | HSPB1 | 204 | 38.5 | 7/13 | 6.0 | 111538 | 89278 | 84258 | 95025 | 8383 |
| Heat shock protein HSP 90-alpha | P07900 | HSP90AA1 | 756 | 20.5 | 13/36 | 4.9 | 251797 | 298927 | 299546 | 283423 | 15814 |
| Heat shock protein HSP 90-beta | P08238 | HSP90AB1 | 771 | 25.7 | 16/44 | 5.0 | 192504 | 242048 | 217251 | 217268 | 14302 |
| Hemoglobin subunit alpha | P69905 | HBA1 | 65 | 10.6 | 1/3 | 8.7 | 5858 | 9805 | 8328 | 7997 | 1151 |
| Heterogeneous nuclear ribonucleoprotein A1 | P09651 | HNRNPA1 | 180 | 25.5 | 6/8 | 9.2 | 27144 | 24090 | 23505 | 24913 | 1128 |
| Heterogeneous nuclear ribonucleoprotein A3 | P51991 | HNRNPA3 | 54 | 3.4 | 1/2 | 9.1 | NA | NA | NA | NA | NA |
| Heterogeneous nuclear ribonucleoprotein D0 | Q14103 | HNRNPD | 37 | 12.4 | 3/4 | 7.6 | 8847 | 7827 | 12568 | 9748 | 1441 |
| Heterogeneous nuclear ribonucleoprotein H | P31943 | HNRNPH1 | 256 | 12.5 | 4/11 | 5.9 | 26946 | 25624 | 23427 | 25333 | 1026 |
| Heterogeneous nuclear ribonucleoprotein H3 | P31942 | HNRNPH3 | 139 | 4.9 | 1/2 | 6.4 | 6109 | 6304 | 3023 | 5145 | 1062 |
| Heterogeneous nuclear ribonucleoprotein K | P61978 | HNRNPK | 146 | 19.7 | 7/10 | 5.4 | 38622 | 17556 | 17898 | 24692 | 6966 |
| Heterogeneous nuclear ribonucleoprotein M | P52272 | HNRNPM | 59 | 12.3 | 7/8 | 8.8 | 5758 | 21460 | 9153 | 12124 | 4770 |
| Heterogeneous nuclear ribonucleoprotein Q | O60506 | SYNCRIP | 65 | 4.2 | 2/6 | 8.7 | 13745 | 23603 | 21745 | 19698 | 3024 |
| Heterogeneous nuclear ribonucleoprotein R | O43390 | HNRNPR | 76 | 4.1 | 2/3 | 8.2 | 9155 | 10674 | 8635 | 9488 | 612 |
| Heterogeneous nuclear ribonucleoprotein U | Q00839 | HNRNPU | 159 | 9.9 | 6/10 | 5.8 | 5461 | 10594 | 6729 | 7594 | 1544 |
| Heterogeneous nuclear ribonucleoproteins A2/B1 | P22626 | HNRNPA2B1 | 231 | 14.7 | 4/19 | 9.0 | 13444 | 15814 | 31249 | 20169 | 5582 |
| Heterogeneous nuclear ribonucleoproteins C1/C2 | P07910 | HNRNPC | 66 | 5.9 | 2/5 | 5.0 | NA | NA | NA | NA | NA |
| Histone H1.0 | P07305 | H1F0 | 38 | 8.2 | 2/2 | 10.8 | 5480 | 3885 | 10012 | 6459 | 1835 |
| Histone H1.3 | P16402 | HIST1H1D | 258 | 15.8 | 4/11 | 11.0 | NA | NA | NA | NA | NA |
| Histone H1.4 | P10412 | HIST1H1E | 251 | 21.5 | 4/8 | 11.0 | 30814 | 21041 | 47941 | 33265 | 7862 |
| Histone H1.5 | P16401 | HIST1H1B | 56 | 6.6 | 2/3 | 10.9 | 41092 | 43699 | 38926 | 41239 | 1380 |
| Histone H2A type 1-B/E | P04908 | HIST1H2AB | 807 | 23.1 | 2/14 | 11.1 | 226485 | 254958 | 230893 | 237445 | 8848 |
| Histone H2A type 1-D | P20671 | HIST1H2AD | 962 | 23.1 | 2/18 | 10.9 | NA | NA | NA | NA | NA |
| Histone H2B type 1-B | P33778 | HIST1H2BB | 3114 | 41.3 | 6/528 | 10.3 | NA | NA | NA | NA | NA |
| Histone H2B type 1-C/E/F/G/I | P62807 | HIST1H2BC | 2764 | 35.7 | 5/97 | 10.3 | NA | NA | NA | NA | NA |
| Histone H2B type 1-M | Q99879 | HIST1H2BM | 3154 | 46 | 7/565 | 10.3 | NA | NA | NA | NA | NA |
| Histone H3.1t | Q16695 | HIST3H3 | 218 | 23.5 | 5/18 | 11.1 | NA | NA | NA | NA | NA |
| Histone H4 | P62805 | HIST1H4A | 1618 | 55.3 | 8/193 | 11.4 | 434182 | 394339 | 417448 | 415323 | 11550 |
| Importin subunit beta-1 | Q14974 | KPNB1 | 54 | 6.1 | 4/5 | 4.7 | 15112 | 13386 | 11843 | 13447 | 944 |
| Importin-9 | Q96P70 | IPO9 | 28 | 2.7 | 1/1 | 4.7 | NA | NA | NA | NA | NA |
| Inosine-5′-monophosphate dehydrogenase 2 | P12268 | IMPDH2 | 56 | 4.5 | 2/3 | 6.4 | 7785 | 13828 | 8262 | 9958 | 1940 |
| Interleukin enhancer-binding factor 3 | Q12906 | ILF3 | 74 | 5.1 | 3/4 | 8.9 | 3331 | 2907 | 5355 | 3864 | 755 |
| Kelch-like protein 35 | Q6PF15 | KLHL35 | 44 | 1.2 | 1/32 | 8.1 | 124565 | 146490 | 86916 | 119324 | 17396 |
| Keratin, type I cytoskeletal 18 | P05783 | KRT18 | 468 | 37.4 | 11/22 | 5.3 | 124666 | 108627 | 93075 | 108789 | 9120 |
| Keratin, type II cytoskeletal 1b | Q7Z794 | KRT77 | 39 | 6.6 | 2/11 | 5.7 | 5480 | 3885 | 10012 | 6459 | 1835 |
| Keratin, type II cytoskeletal 7 | P08729 | KRT7 | 495 | 26.2 | 11/27 | 5.4 | 119134 | 129076 | 105812 | 118007 | 6739 |
| Keratin, type II cytoskeletal 8 | P05787 | KRT8 | 651 | 36.6 | 17/39 | 5.5 | 185098 | 187010 | 191185 | 187764 | 1797 |
| Laminin subunit beta-1 | P07942 | LAMB1 | 35 | 3.5 | 5/7 | 4.8 | NA | NA | NA | NA | NA |
| l-lactate dehydrogenase A chain | P00338 | LDHA | 343 | 25.9 | 8/16 | 8.4 | 108915 | 111146 | 97752 | 105938 | 4143 |
| l-lactate dehydrogenase B chain | P07195 | LDHB | 807 | 24.3 | 7/21 | 5.7 | 170067 | 174272 | 155237 | 166525 | 5773 |
| Lysine-specific demethylase 2B | Q8NHM5 | KDM2B | 39 | 1.8 | 3/4 | 8.9 | NA | NA | NA | NA | NA |
| Macrophage migration inhibitory factor | P14174 | MIF | 45 | 30.4 | 2/3 | 7.7 | 11233 | 6627 | 11216 | 9692 | 1532 |
| Malignant T-cell-amplified sequence 1 | Q9ULC4 | MCTS1 | 73 | 9.4 | 1/3 | 9.0 | 20802 | 17649 | 15260 | 17904 | 1605 |
| Moesin | P26038 | MSN | 910 | 30.8 | 16/45 | 6.1 | 144752 | 101440 | 138689 | 128294 | 13540 |
| Myosin light polypeptide 6 | P60660 | MYL6 | 155 | 29.1 | 3/6 | 4.6 | NA | NA | NA | NA | NA |
| Myosin-9 | P35579 | MYH9 | 497 | 13.2 | 17/51 | 5.5 | 149595 | 188171 | 197928 | 178565 | 14756 |
| Myristoylated alanine-rich C-kinase substrate | P29966 | MARCKS | 99 | 6.9 | 1/2 | 4.5 | NA | NA | NA | NA | NA |
| Nascent polypeptide-associated complex subunit alpha, muscle-specific form | E9PAV3 | NACA | 140 | 2.5 | 3/5 | 9.6 | 19674 | 4499 | 5443 | 9872 | 4908 |
| Neuroblast differentiation-associated protein AHNAK | Q09666 | AHNAK | 55 | 3.7 | 18/33 | 5.8 | 11644 | 14467 | 15574 | 13895 | 1170 |
| Non-POU domain-containing octamer-binding protein | Q15233 | NONO | 40 | 4.9 | 1/2 | 9.0 | NA | NA | NA | NA | NA |
| Nuclear autoantigenic sperm protein | P49321 | NASP | 25 | 2.9 | 1/1 | 4.3 | NA | NA | NA | NA | NA |
| Nucleolin | P19338 | NCL | 334 | 19.9 | 9/25 | 4.6 | 5066 | 3357 | 3897 | 4107 | 504 |
| Nucleophosmin | P06748 | NPM1 | 633 | 25.5 | 6/23 | 4.6 | 84527 | 48445 | 63459 | 65477 | 10465 |
| Nucleoside diphosphate kinase A | P15531 | NME1 | 182 | 28.9 | 3/14 | 5.8 | NA | NA | NA | NA | NA |
| Nucleosome assembly protein 1-like 1 | P55209 | NAP1L1 | 208 | 9 | 2/5 | 4.4 | 14940 | 17948 | 17631 | 16840 | 954 |
| Obg-like ATPase 1 | Q9NTK5 | OLA1 | 56 | 7.1 | 2/3 | 7.6 | 13317 | 6615 | 5783 | 8572 | 2385 |
| Parathymosin | P20962 | PTMS | 85 | 11.8 | 1/2 | 4.1 | NA | NA | NA | NA | NA |
| Peptidyl-prolyl cis-trans isomerase A | P62937 | PPIA | 926 | 58.2 | 9/46 | 7.7 | 334903 | 328382 | 274086 | 312457 | 19278 |
| Peptidyl-prolyl cis-trans isomerase B | P23284 | PPIB | 227 | 22.7 | 4/8 | 9.4 | 52652 | 43189 | 45463 | 47101 | 2852 |
| Peroxiredoxin-1 | Q06830 | PRDX1 | 167 | 49.2 | 10/18 | 8.3 | 41901 | 37568 | 40305 | 39925 | 1265 |
| Peroxiredoxin-6 | P30041 | PRDX6 | 50 | 12.5 | 2/3 | 6.0 | 2427 | 2418 | 2925 | 2590 | 168 |
| Phosphoglycerate kinase 1 | P00558 | PGK1 | 362 | 26.9 | 8/17 | 8.3 | 42360 | 48337 | 45011 | 45236 | 1729 |
| Phosphoglycerate mutase 1 | P18669 | PGAM1 | 147 | 17.7 | 3/8 | 6.7 | NA | NA | NA | NA | NA |
| Plasminogen activator inhibitor 2 | P05120 | SERPINB2 | 48 | 6.7 | 2/3 | 5.5 | 28677 | 19043 | 12147 | 19956 | 4793 |
| Plastin-3 | P13797 | PLS3 | 107 | 12.4 | 5/13 | 5.4 | 46429 | 52915 | 66457 | 55267 | 5900 |
| Plectin | Q15149 | PLEC | 512 | 11.9 | 45/72 | 5.7 | 335859 | 212029 | 106429 | 218106 | 66300 |
| Poly(rC)-binding protein 2 | Q15366 | PCBP2 | 131 | 14.2 | 4/7 | 6.3 | NA | NA | NA | NA | NA |
| Polymerase I and transcript release factor | Q6NZI2 | CAVIN1 | 205 | 9 | 3/5 | 5.5 | 31186 | 37049 | 22373 | 30203 | 4265 |
| Polypyrimidine tract-binding protein 1 | P26599 | PTBP1 | 37 | 3.8 | 1/2 | 9.2 | NA | NA | NA | NA | NA |
| PRA1 family protein 3 | O75915 | ARL6IP5 | 102 | 14.9 | 2/3 | 9.8 | NA | NA | NA | NA | NA |
| Prelamin-A/C | P02545 | LMNA | 756 | 29.4 | 16/31 | 6.6 | 199768 | 214589 | 195265 | 203207 | 5837 |
| Probable ATP-dependent RNA helicase DDX17 | Q92841 | DDX17 | 42 | 8.2 | 5/6 | 8.5 | NA | NA | NA | NA | NA |
| Probable ATP-dependent RNA helicase DDX5 | P17844 | DDX5 | 102 | 4.4 | 2/4 | 9.1 | 70159 | 72621 | 63348 | 68709 | 2773 |
| Profilin-1 | P07737 | PFN1 | 158 | 61.4 | 8/13 | 8.4 | 52591 | 56414 | 50850 | 53285 | 1643 |
| Prohibitin | P35232 | PHB | 32 | 3.7 | 1/4 | 5.6 | 7468 | 7390 | 4636 | 6498 | 931 |
| Prohibitin-2 | Q99623 | PHB2 | 40 | 4 | 1/1 | 9.8 | 2140 | 4504 | 3240 | 3295 | 683 |
| Proliferating cell nuclear antigen | P12004 | PCNA | 41 | 16.9 | 3/4 | 4.6 | 12659 | 20827 | 15557 | 16348 | 2391 |
| Proliferation-associated protein 2G4 | Q9UQ80 | PA2G4 | 55 | 6.3 | 2/3 | 6.1 | 10199 | 14511 | 10920 | 11877 | 1333 |
| Proteasome activator complex subunit 2 | Q9UL46 | PSME2 | 85 | 5.4 | 1/2 | 5.5 | 11756 | 6448 | 7849 | 8684 | 1588 |
| Protein disulfide-isomerase A3 | P30101 | PDIA3 | 160 | 17 | 6/9 | 6.0 | 23578 | 27498 | 24887 | 25321 | 1152 |
| Protein disulfide-isomerase A4 | P13667 | PDIA4 | 59 | 3.4 | 2/3 | 5.0 | 14875 | 5481 | 10585 | 10314 | 2715 |
| Protein disulfide-isomerase A6 | Q15084 | PDIA6 | 176 | 16.4 | 4/8 | 5.0 | 35284 | 43729 | 28531 | 35848 | 4396 |
| Protein S100-A10 | P60903 | S100A10 | 101 | 45.4 | 3/6 | 6.8 | NA | NA | NA | NA | NA |
| Protein S100-A11 | P31949 | S100A11 | 1157 | 34.3 | 3/41 | 6.6 | 98925 | 46580 | 67624 | 71043 | 15207 |
| Protein S100-A6 | P06703 | S100A6 | 65 | 16.7 | 2/4 | 5.3 | 14068 | 16731 | 7122 | 12641 | 2864 |
| Protein transport protein Sec61 subunit beta | P60468 | SEC61B | 40 | 20.8 | 2/2 | 11.6 | NA | NA | NA | NA | NA |
| Protein-glutamine gamma-glutamyltransferase 2 | P21980 | TGM2 | 280 | 16.4 | 8/12 | 5.1 | 42175 | 39248 | 42729 | 41384 | 1080 |
| Prothymosin alpha | P06454 | PTMA | 125 | 12.6 | 1/2 | 3.7 | NA | NA | NA | NA | NA |
| Proto-oncogene serine/threonine-protein kinase mos | P00540 | MOS | 42 | 6.4 | 2/235 | 9.2 | 162044 | 123745 | 169678 | 151822 | 14211 |
| Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | P11177 | PDHB | 68 | 7.5 | 2/3 | 6.2 | 50008 | 38284 | 38838 | 42377 | 3819 |
| Pyruvate kinase PKM | P14618 | PKM | 1981 | 56.9 | 24/145 | 8.0 | 541639 | 405570 | 446687 | 464632 | 40291 |
| Rab GDP dissociation inhibitor beta | P50395 | GDI2 | 85 | 4.9 | 2/7 | 6.1 | 14841 | 13465 | 10350 | 12886 | 1329 |
| Ras-related C3 botulinum toxin substrate 1 | P63000 | RAC1 | 45 | 15.6 | 3/4 | 8.8 | NA | NA | NA | NA | NA |
| Ras-related protein Rab-10 | P61026 | RAB10 | 84 | 20 | 3/4 | 8.6 | NA | NA | NA | NA | NA |
| Ras-related protein Rab-1B | Q9H0U4 | RAB1B | 37 | 21.4 | 3/5 | 5.6 | NA | NA | NA | NA | NA |
| Ras-related protein Rab-7a | P51149 | RAB7A | 41 | 6.8 | 1/2 | 6.4 | 9007 | 10021 | 8229 | 9086 | 519 |
| Receptor of activated protein C kinase 1 | P63244 | RACK1 | 40 | 4.4 | 2/3 | 7.6 | 1669 | 8683 | 9471 | 6608 | 2480 |
| Rho GDP-dissociation inhibitor 1 | P52565 | ARHGDIA | 113 | 7.4 | 1/2 | 5.0 | 7234 | 3657 | 4415 | 5102 | 1088 |
| Ribosome-binding protein 1 | Q9P2E9 | RRBP1 | 41 | 4.4 | 5/6 | 8.7 | NA | NA | NA | NA | NA |
| RNA-binding protein FUS | P35637 | FUS | 254 | 7.8 | 2/6 | 9.4 | NA | NA | NA | NA | NA |
| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | P36873 | PPP1CC | 48 | 14.2 | 3/5 | 6.1 | 5720 | 13195 | 15886 | 11600 | 3041 |
| Serpin H1 | P50454 | SERPINH1 | 139 | 14.4 | 3/5 | 8.8 | 8221 | 28883 | 39811 | 25638 | 9262 |
| Signal recognition particle 14 kDa protein | P37108 | SRP14 | 171 | 10.3 | 1/2 | 10.1 | NA | NA | NA | NA | NA |
| Small nuclear ribonucleoprotein Sm D1 | P62314 | SNRPD1 | 75 | 16.8 | 1/5 | 11.6 | 36616 | 14165 | 13818 | 21533 | 7542 |
| Stress-70 protein, mitochondrial | P38646 | HSPA9 | 61 | 10.8 | 6/9 | 5.9 | 42451 | 53345 | 45465 | 47087 | 3248 |
| Sulfotransferase 1A3 | P0DMM9 | SULT1A3 | 83 | 11.2 | 2/4 | 5.7 | NA | NA | NA | NA | NA |
| Surfeit locus protein 4 | O15260 | SURF4 | 113 | 6.7 | 1/4 | 7.6 | NA | NA | NA | NA | NA |
| T-complex protein 1 subunit alpha | P17987 | TCP1 | 31 | 8.1 | 3/3 | 5.8 | NA | NA | NA | NA | NA |
| T-complex protein 1 subunit delta | P50991 | CCT4 | 133 | 5.9 | 3/4 | 8.0 | 2861 | 3278 | 3014 | 3051 | 122 |
| T-complex protein 1 subunit eta | Q99832 | CCT7 | 219 | 8.7 | 2/9 | 7.6 | NA | NA | NA | NA | NA |
| T-complex protein 1 subunit gamma | P49368 | CCT3 | 36 | 11 | 3/3 | 6.1 | NA | NA | NA | NA | NA |
| T-complex protein 1 subunit theta | P50990 | CCT8 | 107 | 5.8 | 2/4 | 5.4 | 6878 | 3385 | 19274 | 9846 | 4821 |
| T-complex protein 1 subunit zeta | P40227 | CCT6A | 47 | 11.7 | 5/8 | 6.2 | 22142 | 22782 | 12656 | 19194 | 3274 |
| Thioredoxin domain-containing protein 5 | Q8NBS9 | TXNDC5 | 206 | 13 | 4/6 | 5.6 | 4738 | 41071 | 7478 | 17763 | 11681 |
| Tight junction protein ZO-1 | Q07157 | TJP1 | 27 | 3.7 | 5/8 | 6.2 | NA | NA | NA | NA | NA |
| Transaldolase | P37837 | TALDO1 | 31 | 4.7 | 2/4 | 6.4 | 14850 | 6899 | 7830 | 9860 | 2509 |
| Transcription elongation factor A protein-like 3 | Q969E4 | TCEAL3 | 46 | 20 | 2/3 | 4.9 | NA | NA | NA | NA | NA |
| Transcription factor BTF3 | P20290 | BTF3 | 67 | 24.8 | 2/3 | 9.4 | NA | NA | NA | NA | NA |
| Transgelin-2 | P37802 | TAGLN2 | 605 | 52.8 | 8/26 | 8.4 | 96536 | 82842 | 76076 | 85151 | 6018 |
| Transitional endoplasmic reticulum ATPase | P55072 | VCP | 336 | 10.7 | 6/17 | 5.1 | 48158 | 25146 | 19881 | 31062 | 8682 |
| Transketolase | P29401 | TKT | 611 | 13 | 7/22 | 7.6 | 62407 | 56349 | 45118 | 54624 | 5065 |
| Triosephosphate isomerase | P60174 | TPI1 | 623 | 40.6 | 8/24 | 5.7 | 161006 | 184029 | 208480 | 184505 | 13707 |
| Tropomodulin-3 | Q9NYL9 | TMOD3 | 56 | 9.7 | 2/2 | 5.1 | 3612 | 2492 | 3531 | 3212 | 361 |
| Tropomyosin alpha-1 chain | P09493 | TPM1 | 116 | 15.1 | 3/6 | 4.7 | NA | NA | NA | NA | NA |
| Tropomyosin alpha-4 chain | P67936 | TPM4 | 156 | 18.5 | 4/7 | 4.7 | NA | NA | NA | NA | NA |
| Tubulin alpha-1B chain | P68363 | TUBA1B | 730 | 32.8 | 10/33 | 4.9 | 253775 | 282977 | 235455 | 257402 | 13838 |
| Tubulin beta chain | P07437 | TUBB | 969 | 34.2 | 11/36 | 4.8 | 202837 | 201022 | 190264 | 198041 | 3924 |
| Tubulin beta-4B chain | P68371 | TUBB4B | 929 | 34.2 | 11/34 | 4.8 | NA | NA | NA | NA | NA |
| Tubulin beta-6 chain | Q9BUF5 | TUBB6 | 223 | 24.2 | 8/19 | 4.8 | 98391 | 92260 | 91928 | 94193 | 2101 |
| Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial | Q9Y2Z9 | COQ6 | 35 | 1.9 | 1/234 | 6.8 | 162139 | 124377 | 170237 | 152251 | 14132 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | P09936 | UCHL1 | 58 | 22 | 3/5 | 5.3 | 13815 | 12083 | 9694 | 11864 | 1195 |
| Ubiquitin-40S ribosomal protein S27a | P62979 | RPS27A | 334 | 25.6 | 4/13 | 9.7 | NA | NA | NA | NA | NA |
| Ubiquitin-like modifier-activating enzyme 1 | P22314 | UBA1 | 195 | 8.3 | 5/12 | 5.5 | 94700 | 122097 | 107087 | 107961 | 7921 |
| UPF0258 protein KIAA1024 | Q9UPX6 | KIAA1024 | 30 | 4 | 3/4 | 7.0 | 9236 | 5429 | 3319 | 5995 | 1731 |
| Vimentin | P08670 | VIM | 3693 | 59.4 | 29/320 | 5.1 | 916825 | 966574 | 861243 | 914880 | 30422 |
| Vinculin | P18206 | VCL | 100 | 8.9 | 8/12 | 5.5 | 22380 | 22607 | 10146 | 18378 | 4116 |
| Voltage-dependent anion-selective channel protein 1 | P21796 | VDAC1 | 65 | 17.3 | 4/6 | 8.6 | 18338 | 13894 | 3640 | 11957 | 4352 |
| X-ray repair cross-complementing protein 6 | P12956 | XRCC6 | 232 | 13.5 | 5/11 | 6.2 | 12431 | 22365 | 7683 | 14160 | 4326 |
| Zyxin | Q15942 | ZYX | 32 | 2.1 | 1/1 | 6.2 | 16040 | 8804 | 16016 | 13620 | 2408 |
%Cov = %Sequence coverage = (number of the matched residues/total number of residues in the entire sequence) x 100%.
NA = not applicable (protein was identified in the sample but its MS/MS spectra did not meet predefined criteria for high-confident intensity analysis).