Table 2.
Changes in cardiovascular hemodynamic values and urinary sodium excretion rates immediately after (Stress) and 45 min after (Recovery) mental stress from rest following placebo (PLC) or angiotensin II receptor blocker (ARB) treatment
Variable | PLC | ARB | ||
---|---|---|---|---|
Stress | Recovery | Stress | Recovery | |
ΔSBP (mm Hg) | 3.6 ± 7.9 | 1.6 ± 6.4 | 2.4 ± 7.7 | −1.2 ± 7.3* |
ΔDBP (mm Hg) | 3.0 ± 6.0 | 1.9 ± 5.3 | 2.2 ± 4.9 | −0.1 ± 1.0* |
ΔHR (bpm) | 1.3 ± 6.7 | −4.3 ± 5.7 | 1.9 ± 6.0 | −3.9 ± 5.6 |
ΔSV (mL) | −6.1 ± 11.5 | −3.6 ± 12.5 | −5.4 ± 11.2 | −2.9 ± 9.7 |
ΔTPR (dynes·sec·cm−5) | −78 ± 479 | −29 ± 134 | −75 ± 212 | −10 ± 78 |
ΔCO (L/min) | −0.1 ± 1.0 | −0.5 ± 1.0 | −0.0 ± 1.0 | −0.5 ± 0.8 |
ΔUNaV (mEq/min) | 0.05 ± 0.13 | 0.02 ± 0.17 | 0.09 ± 0.17* | 0.04 ± 0.17 |
Values are mean ± SD.
Abbreviations: Bpm, beats per minute; CO, cardiac output; DBP, diastolic blood pressure; HR, heart rate; SBP, systolic blood pressure; SV, stroke volume; TPR, total peripheral resistance; UNaV, urinary sodium excretion rate.
Significant difference from PLC at the corresponding condition (P < 0.05).