Table 1.
Demographic and treatment characteristics of survivors of pediatric low grade glioma and siblings†
| Variable | Surgery-only (N=85) | Surgery+RT (N=96) | Siblings (N=105) |
|---|---|---|---|
| Sex N (%)† | |||
| Male | 42 (49.4%) | 43 (44.8%) | 38 (36.2%) |
| Female | 43 (50.6%) | 53 (55.2%) | 67 (63.8%) |
| Race/Ethnicity N (%) | |||
| Non-Hispanic White | 79 (92.9%) | 88 (91.7%) | 82 (84.5%) |
| Non-Hispanic Black | 0 (0%) | 1 (1%) | 3 (3.1%) |
| Hispanic | 0 (0%) | 0 (0%) | 3 (3.1%) |
| Other | 6 (7.1%) | 7 (7.3%) | 9 (9.3%) |
| Age-at-diagnosis, Median years (range) |
8.0 (0–18) | 7.0 (0–19) | - |
| Age-at-testing Median years (range) |
40.0 (27–58) | 41(27–58) | 40 (24–60) |
| Tumor location N (%) | |||
| Supratentorial | 26 (37.7%) | 47 (49%) | - |
| Infratentorial | 43 (62.3%) | 49 (51%) | - |
| Chemotherapy N, (%) | 0 | 15 (15.6%) | - |
| Median radiation dose (min,max)‡ | - | 52.5 (36,72) Gy | - |
| Socioeconomic status of the family of origin (Duncan) Median (range)§ |
68.8 (28.2–97.2) | 55.3 (29.4–92.3) | 65.2 (27.5 – 92.8) |
| Participant Occupational Prestige (Duncan) Median (range) | 64.8 (11.1– 97.1) | 37.3 (11.1–93.1) | 63.9 (11.1–93.7) |
| N (%) | |||
| 11.1–48.9 | 26 (38.8%) | 42 (66.7%) | 23 (25%) |
| >48.9–62.9 | 6 (9%) | 8 (12.7%) | 23 (25%) |
| >62.9–79.9 | 19 (28.4%) | 8 (12.7%) | 23 (25%) |
| >79.9–93.7 | 16 (23.9%) | 5 (7.9%) | 23 (25%) |
| No score | 18 (Disabled=8) |
33 (Disabled=19) |
13 (Disabled=0) |
| Participant Income¶ N (%) | |||
| Under $20,000 | 27 (32.1%) | 56 (58.3%) | 28 (26.7%) |
| $20–59,999 | 33 (39.3%) | 31 (32.3%) | 29 (27.6%) |
| ≥$60,000 | 24 (28.6%) | 9 (9.4%) | 48 (45.7%) |
| Unknown | 1 | 0 | 0 |
| Participant Education N (%) | |||
| ≤ High School (HS) | 13 (15.3%) | 19 (19.8%) | 3 (2.9%) |
| ≥ HS to < Bachelor’s Degree | 23 (27.1%) | 42 (43.8%) | 37 (35.2%) |
| Bachelor’s Degree | 27 (31.8%) | 22 (22.9%) | 33 (31.4%) |
| Any Graduate Studies | 22 (25.9%) | 13 (13.5%) | 32 (30.5%) |
†
All percents are evaluated using N for non-missing values as the denominator.
‡
Based upon N=86 for which CCSS has records.
§
Duncan Occupational Prestige is an unequal interval scale with scores ranging from 17 (e.g. laborers, operators) to over 90 (e.g. higher professions and specialty occupations). Occupation category cut points were defined by the quartiles for the sibling population.
¶
Income categories are divided at the cut points for the lower two quartiles of siblings, with upper two quartiles combined due to low numbers among survivors.