Table 3:

Odds of positive QuantiFERON-TB Gold-in-Tube by parasite group, epidemiologic study

Characteristic	Crude OR	95% CI	aOR†	95% CI	aOR‡	95% CI
Parasites Detected
None (n=293)	Ref	Ref	Ref	Ref	Ref	Ref
B. hominis (n=70)	1.16	(0.66, 2.06)	1.12	(0.49, 2.56)	1.19	(0.65, 2.18)
Other Protozoa (n=81)	1.28	(0.75, 2.18)	1.44	(0.70, 2.98)	1.46	(0.82, 2.60)
Helminth (n=27)	0.77	(0.30, 1.99)	0.47	(0.10, 2.19)	0.61	(0.23, 1.64)
Age
Children (<18yo)	Ref	Ref	Ref	Ref	Ref	Ref
Adults (≥18yo)	7.25	(3.08, 17.0)	8.44	(2.81, 25.4)	9.19	(3.80, 22.2)
Time since arrival to US
<12 weeks	Ref	Ref
≥ 12 weeks	1.26	(0.63, 2.53)
Sex
Male	Ref	Ref
Female	0.63	(0.41, 0.96)
BMI
Underweight	Ref	Ref
Normal Weight	1.94	(0.92, 4.08)
Overweight/Obese	3.59	(1.73, 7.44)
Alcohol use
Yes	2.67	(1.32, 5.38)	1.43	(0.60, 3.40)
No	Ref	Ref	Ref	Ref
Tobacco use
Yes	1.94	(1.00, 3.77)	2	(0.79, 5.04)
No	Ref	Ref	Ref	Ref
Mean TB incidence, country of origin, cases per 100,000	1.004	(1.002, 1.006)	1.006	(1.003, 1.009)	1.01	(1.003, 1.007)
Pre-departure anti-helminthic treatment
Yes	1.11	(0.74, 1.66)
No	Ref	Ref
HIV
Yes	4.69	(1.10, 19.9)	10.24	(1.01, 104)
No	Ref	Ref	Ref	Ref
Pregnant
Yes	0.4	(0.05, 3.37)	0.4	(0.04, 3.58)
No	Ref	Ref	Ref	Ref
Diabetes Mellitus
Yes	2.66	(0.91, 7.72)
No	Ref	Ref
Absolute Eosinophil Count (cells/hpf)	0.68	(0.26, 1.80)	0.3	(0.04, 2.10)

^*Total No. for this table is 471 (Those with mixed B. hominis and other protozoa detected [n=51] or indeterminate QGIT results [n=5] were excluded from multivariable analysis).

^†OR of positive compared to negative QGIT adjusted for age (≥18 vs. <18), alcohol use, tobacco use, tuberculosis incidence of country of origin, absolute eosinophil count, pregnancy, and HIV.

^‡Using multiple imputation analysis to account for all missing data, OR of positive vs. negative QGIT adjusted for age (≥18 vs. <18) and tuberculosis incidence of country of origin.

Abbreviations: QGIT QuantiFERON-TB Gold In-Tube aOR Adjusted Odds Ratio CI Confidence Interval