Table 1.
Significantly enriched gene ontology terms related to differentially expressed astrocyte-associated genes.
| Hierarchical cluster* | Gene ontology terms | Number of genes | FDR [%] |
|---|---|---|---|
| A | Not assigned | ||
| B | immune system process | 22 | <0.1 |
| positive regulation of immune system process | 15 | <0.1 | |
| apoptotic process | 14 | 0.1 | |
| positive regulation of signal transduction | 13 | 0.3 | |
| C | response to cytokine | 5 | 0.3 |
| D | Not assigned |
*Hierarchical clusters refer to the respective cluster of genes with a similar expression pattern obtained from hierarchical cluster analysis as displayed in Fig. 5A. Functional annotation was performed for each hierarchical cluster and specific gene ontology terms that subjectively gave the best description of the cluster and met the cut-off criteria of FDR ≤ 1.0% were selected.