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. 2019 Aug 12;5:28. doi: 10.1038/s41540-019-0106-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — TFA network (FDCRNet) construction workflow for Flower Development and Circadian Rhythm processes. Key molecules (TFs) for circadian rhythm and flower development are curated from GO annotation database. Functional linkage and gene expression data are integrated step-by-step to construct the transcriptional regulation network, modulation regulatory network, and TFA network for those key molecules