Fig. 3.

TF activity is more accurate than the TF’s mRNA expression. a A gene regulatory network for flower development and circadian rhythm by correlating TF and target genes. The blue score and red score on edges represent the mutual information computed by TF’s mRNA expression and TF activity, respectively. b Comparison of the distributions of the mutual information computed by mRNA expression and TF activity on each edge of the standard network. The green box and blue box represent the distributions of the mutual information computed by mRNA expression and TF activity, respectively. c Comparison of conditional mutual information on two groups of Modulator–TF–TG triplets, selected by TF activity or by TF’s mRNA expression. Note that all triplets used in comparison have significant conditional mutual information