Table 1.

Inhibitors with different functions used in the transport study and their concentrations

Inhibitors	Concentrations	Functions
Act D	3.2 μM	Inhibitor of ASBT-mediated transport
Chlorpromazine	32 μM	Inhibitor of clathrin-mediated endocytosis
MβCD	10 mM	Inhibitor of caveola/lipid raft-mediated endocytosis (cholesterol depletion agent)
Genistein	0.1 mM	Inhibitor of caveola/lipid raft-mediated endocytosis (broad inhibitor of protein tyrosine kinase)
Amiloride	0.1 mM	Inhibitor of macropinocytosis
Cyclosporine A	10 mM	Inhibitor of P-gp mediated efflux
Brefeldin A	90 μM	Inhibitor of ER/Golgi pathway

Abbreviations: Act D, actinomycin D; MβCD, methyl-β-cyclodextrin; ASBT, apical sodium-dependent bile acid transporter; P-gp, P-glycoprotein; ER, endoplasmic reticulum.