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. 2019 Aug 12;9:11695. doi: 10.1038/s41598-019-48081-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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VitD restores EVE sensitivity in HCC EveR cells. Cell proliferation evaluated by DNA assay in PLC/PRF/5 and JHH-6 EveR after 12 and 24 hrs of pre-treatment with VitD and 6 days of co-treatment with EVE. The data presented are mean ± SEM of three independent experiments. ^####p < 0.0001 vs control plus DMSO; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs control plus DMSO and EtOH; °p < 0.05, °°p < 0.01, °°°p < 0.001, °°°°p < 0.0001 between groups.