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. 2019 Aug 12;9:11674. doi: 10.1038/s41598-019-47943-6

Table 2.

Patient characteristics in non-ACLD and ACLD patients.

No statin despite indication On statin therapy No indication for statin p-value
non-ACLD
# of patients 55 106 577
Age [years] 55.4 (17.4) 58.0 (14.6) 46.0 (20.68) <0.001
CAP [dB/m] 252 (98) 274.5 (80.3) 242 (87) <0.001
BMI [kg/m²] 26.2 (8.4) 27.0 (8.1) 25.2 (6.0) 0.003
Male sex (%) 29 (52.7%) 58 (54.7%) 309 (53.6%) 0.969
Arterial hypertension (%) 30 (54.5%) 77 (72.6%) 116 (20.1%) <0.001
NIDDM (%) 24 (43.6%) 33 (31.1%) 11 (1.9%) <0.001
IDDM (%) 3 (5.5%) 6 (5.7%) 12 (2.1%)
(N)AFLD 23 (41.8%) 55 (51.9%) 181 (31.4%) <0.001
Cholestatic LD 3 (5.5%) 8 (7.5%) 13 (2.3%)
Hepatitis C 16 (29.1%) 20 (18.9%) 199 (34.5%)
Hepatitis B 3 (5.5%) 4 (3.8%) 31 (5.4%)
Other LD 10 (18.2%) 19 (17.9%) 153 (26.5%)
ACLD
# of patients 67 72 388
Age [years] 60.4 (15.0) 60.8 (10.6) 54.3 (14.7) <0.001
CAP [dB/m] 290 (85) 299 (130) 247 (96) <0.001
BMI [kg/m²] 29.7 (5.8) 28.4 (7.9) 26.4 (6.5) <0.001
Male sex (%) 43 (64.2%) 50 (69.4%) 249 (64.2%) 0.685
Arterial hypertension (%) 42 (62.7%) 49 (68.1%) 100 (25.8%) <0.001
NIDDM (%) 39 (58.2%) 28 (38.9%) 25 (6.4%) <0.001
IDDM (%) 7 (10.4%) 12 (16.7%) 38 (9.8%)
(N)AFLD 29 (43.3%) 29 (40.3%) 88 (22.7%) 0.001
Cholestatic LD 0 (0.0%) 1 (1.4%) 9 (2.3%)
Hepatitis C 31 (46.3%) 29 (40.3%) 223 (57.5%)
Hepatitis B 0 (0.0%) 5 (6.9%) 12 (3.1%)
Other LD 7 (10.4%) 8 (11.1%) 56 (14.4%)

CAP = controlled attenuation parameters; BMI = body-mass index, NIDDM = non-insulin dependent diabetes mellitus; IDDM = insulin-dependent diabetes mellitus; LD = liver disease.