FIGURE 7.

Electric field levels predicted at the basilar membrane by the computational simulation of array-driven electroporation in the guinea pig cochlea. (A) The electric field is categorized into different levels and the area on the basilar membrane subjected fallen within each level is plotted at each sample time point. Two electrode configurations are considered: alternate and tandem, and in both cases a single 20 V, 50 ms pulse was applied with 1 ms rise and fall times. (B) A comparison of the areas at each electric field level obtained using the tandem electroporation configuration relative to the alternate configuration.