Table 4. Univariable analysis and multivariable analysis for disease-free survival.
| Characteristic | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| Odds (95% CI) | P value | Odds (95% CI) | P value | ||
| Age | 1.001 (0.995–1.007) | 0.799 | |||
| Sex | 1.191 (0.991–1.431) | 0.062 | |||
| Comorbid | 1.081 (0.937–1.248) | 0.284 | |||
| Child Pugh grade | 1.262 (0.871–1.829) | 0.219 | |||
| Ascites | 2.989 (1.239–7.211) | 0.015 | 2.48 (1.02–6.02) | 0.045 | |
| AFP | |||||
| <20 | – | – | |||
| 20–400 | 1.36 (1.14–1.62) | 0.001 | 1.19 (0.99–1.42) | 0.065 | |
| >400 | 1.8 (1.52–2.13) | <0.001 | 1.34 (1.12–1.61) | 0.001 | |
| Bilirubin | 1.0006 (0.997–1.016) | 0.207 | |||
| Platelet | 1 (0.999–1.001) | 0.434 | |||
| INR | 3.848 (1.883–7.863) | <0.001 | |||
| Albumin | 0.943 (0.929–0.958) | <0.001 | 0.97 (0.95–0.98) | <0.001 | |
| Preop ICG (>15) | 1.207 (1.023–1.425) | 0.026 | |||
| No. of tumors (solitary vs. multiple) | 2.577 (2.214–2.998) | <0.001 | 2 (1.7–2.34) | <0.001 | |
| Size of largest tumor (cm) | 1.072 (1.058–1.086) | <0.001 | 1.03 (1.02–1.05) | <0.001 | |
| Magnitude of operation (major vs. minor) | 1.365 (1.183–1.575) | <0.001 | |||
| Intraop blood loss | 1.087 (1.047–1.129) | <0.001 | |||
| Blood transfusion | 1.507 (1.231–1.846) | <0.001 | |||
| Invasion into major branch/hepatic vein | 2.664 (2.087–3.402) | <0.001 | |||
| Invasion into adjacent organ | 1.925 (1.351–2.744) | <0.001 | |||
| Microvascular invasion | 2.202 (1.906–2.543) | <0.001 | 1.69 (1.44–1.97) | <0.001 | |
| Differentiation | |||||
| Well | – | – | |||
| Moderate | 1.317 (1.086–1.598) | 0.005 | |||
| Poor | 1.634 (1.303–2.048) | <0.001 | |||
| UICC staging (I/II vs. III/IV) | 2.66 (2.286–3.095) | <0.001 | |||
AFP, alpha-fetoprotein; ICG, indocyanine green; UICC, Union for International Cancer Control.