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. 2019 Aug 6;10:1810. doi: 10.3389/fmicb.2019.01810

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Copyright © 2019 Yang, Wang, Zhuge, Zhang, Xu, Zhang, Zhang, Chen, Chu and Jia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of HA treatment on cell membrane in C. albicans cells. (A) The changes of cell membrane potential were assessed in HA-treated C. albicans cells using DiBAC₄ (3) staining. The histogram was the quantitative analysis of DiBAC₄ (3)-positive cells, and data were exhibited as mean ± SD (n = 3). ^*P < 0.05 and ^∗∗P < 0.01. (B) Cell membrane integrity was evaluated using PI staining. The percentage of PI-positive cells was displayed in the histogram, and data were shown mean ± SD (n = 3). ^*P < 0.05 and ^∗∗P < 0.01.