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. 2019 Aug 6;10:522. doi: 10.3389/fendo.2019.00522

Table 2.

Adverse perinatal outcomes in women with SCH.

Outcome SCH (n, %) CON (n, %) Unadjusted Adjusted*
OR 95% CI P OR 95% CI P
Gestational diabetes 25, 15.15% 342, 11.70% 1.30 0.89–1.88 0.18 1.05 0.0.66–1.69 0.84
HDP 9, 5.45% 43, 1.47% 3.71 1.84–7.48 0.001 4.04 1.85–8.84 0.000
ICP 2, 1.21% 21, 0.72% 1.69 0.40–7.13 0.47 1.72 0.40–7.42 0.47
Preterm labor 6, 3.64% 119, 4.07% 0.89 0.40–2.00 0.78 0.27 0.04–1.95 0.19
Placenta previa 9, 5.45% 104, 3.56% 1.53 0.79–2.97 0.21 1.53 0.76–3.09 0.23
PROM 37, 22.42% 476, 16.28% 1.38 1.03–1.85 0.04 1.41 0.96–2.05 0.08
FGR 0, 0.00% 12, 0.41%
Fetal distress 1, 0.61% 16, 0.55% 1.11 0.15–8.30 0.92 1.06 0.14–8.08 0.95
Fetal death 1, 0.61% 7, 0.24% 2.53 0.31–20.45 0.37 1.49 0.55–4.03 0.43
Apgar < 7 3, 1.82% 18, 0.62% 2.95 0.88–9.92 0.07 1.76 0.53–5.84 0.35
Birth weight < 2,500 g 2, 1.21% 80, 2.74% 0.44 0.11–1.79 0.24 0.43 0.11–1.77 0.24
Birth weight more than 4,000 g 11, 6.67% 156, 5.34% 1.25 0.69–2.26 0.46 1.28 0.68–2.41 0.44
*

Adjusted for race. HDP, hypertensive disorders of pregnancy; ICP, intrahepatic cholestasis of pregnancy; PROM, preterm premature rupture of membranes; FGR, fetal growth restriction.