Table 4.
Quality of life (ITT populationa).
| Baseline (Mean ± SD) | End of chemotherapy (Mean ± SD) | 12 weeks after end of chemotherapy (Mean ± SD) | |||||
|---|---|---|---|---|---|---|---|
| Scalp cooling n = 32 | Control n = 14 | Scalp cooling n = 30 | Control n = 12 | P-valueb | Scalp cooling n = 28 | Control n = 12 | |
| EORTC QLQ-C30 SCORE | |||||||
| Global health status | 72.66 ± 18.84 | 69.64 ± 18.38 | 62.22 ± 23.64 | 51.39 ± 21.86 | 0.179 | 65.77 ± 26.77 | 65.28 ± 22.14 |
| Emotional functioning | 81.25 ± 13.39 | 77.98 ± 18.95 | 84.44 ± 13.97 | 81.25 ± 13.82 | 0.506 | 86.90 ± 16.58 | 84.03 ± 15.27 |
| Social functioning | 90.10 ± 15.18 | 86.90 ± 13.36 | 77.22 ± 17.77 | 68.06 ± 21.86 | 0.165 | 85.71 ± 14.85 | 84.72 ± 13.22 |
| HADS SCORE | |||||||
| Anxiety summary | 8.88 ± 1.88 | 9.00 ± 2.57 | 8.00 ± 2.17 | 8.42 ± 2.27 | 0.582 | 7.89 ± 2.02 | 8.08 ± 2.02 |
| Depression summary | 9.72 ± 1.30 | 9.50 ± 1.99 | 9.17 ± 1.90 | 9.83 ± 1.99 | 0.316 | 8.64 ± 1.68 | 9.17 ± 1.40 |
a
The ITT population was defined as patients who received at least one cycle of chemotherapy without a major protocol violation.
b
T-test (two-sided).