Table 2.

Univariate Cox regression analysis of the risk factors in colorectal cancer.

Clinicopathologic features	OS			DFS
	HR	95% CI	P	HR	95% CI	P
Gender (male/female)	0.869	0.518–1.457	0.594	1.028	0.591–1.789	0.923
Age (≤60/>60)	0.915	0.550–1.522	0.733	0.709	0.404–1.244	0.230
Tumor size (cm) (>4.3/ ≤ 4.3)	1.596	0.959–2.655	0.072	1.456	0.840–2.524	0.181
Differentiation degree (well/moderate + poor)	0.901	0.530–1.532	0.700	1.054	0.600–1.850	0.855
T-stage (T3 + T4/T1 + T2)	9.112	2.224–37.343	0.002	15.330	2.117–111.036	0.007
N-stage (N1 + N2/N0)	4.047	2.359–6.944	0.000	3.369	1.902–5.967	0.000
M-stage (M1/M0)	6.456	2.304–18.902	0.000	7.305	2.246–23.760	0.001
Nerve invasion (positive/negative)	2.838	1.674–4.811	0.000	2.442	1.358–4.390	0.003
Vascular invasion (positive/negative)	2.015	1.210–3.355	0.007	1.995	1.148–3.465	0.014
TNM stage (III + IV/I + II)	4.332	2.507–7.487	0.000	3.333	1.881–5.905	0.000
NAPRT (high/low)	2.622	1.459–4.713	0.001	2.765	1.468–5.210	0.002
NAMPT (high/low)	3.518	2.085–5.935	0.000	3.05	1.743–5.337	0.000

OS, overall survival; DFS, disease- free survival. The bold values indicated that the P-value was smaller than 0.05.