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. 2019 Aug 6;10:1800. doi: 10.3389/fmicb.2019.01800

FIGURE 4.

FIGURE 4

Dectin-1 mediates Candida clearance. (A,B) WT and Dectin-1 KO mice were infected intravenously with the indicated doses of C. albicans, C. glabrata, C. tropicalis or C. parapsilosis for 7 days. (A) CFU in the kidneys and brains of mice at 7 days post-infection were determined. Graphs are the cumulative result of 2–4 independent experiments. Each symbol represents an individual mouse. Student’s t test (C. albicans: transformed data) (B) Cytokine levels in the serum of mice at 7 days post-infection. Graphs are the cumulative result of 2–4 independent experiments. Each symbol represents an individual mouse. Student’s t test/ Mann-Whitney test (IL-6, TNF, IL-1β, IL-10: transformed data).