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Effect of BNN on intracellular ROS accumulation. (A and B) BNN induced ROS production in a dose-dependent manner following treatment with 10, 20 and 40 µM BNN for 24 h. *P<0.05 and **P<0.01 vs. DMSO. (C and D) BNN-induced ROS accumulation was inhibited by the PPARγ antagonists T0070907 and GW9662. Magnification, ×200. **P<0.01, as indicated. BNN, bavachinin; ROS, reactive oxygen species; PPARγ, peroxisome proliferator-activated receptor γ.
