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. 2019 Jul 1;20(3):2236–2244. doi: 10.3892/mmr.2019.10447

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — miR-330-5p is downregulated in OS tissues and cell lines. (A) miR-330-5p expression was measured by RT-qPCR in tumor tissues (n=63) and control osteochondroma tissues (n=20). (B) miR-330-5p expression was measured in OS tissues with or without distant metastasis by RT-qPCR. (C) Kaplan-Meier survival curve demonstrated the association between the overall survival of osteosarcoma patients and the miR-330-5p levels. (D) miR-330-5p expression was detected in the HOS, U2OS and MG63 cells, and normal hFOB1.19 cells were used as the control. Data represent the mean ± standard deviation of three independent experiments. **P<0.01 vs. hFOB1.19 cells. miR, microRNA; OS, osteosarcoma; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.