Table I.
Clinicopathological characteristics of patients with T-cell lymphoblastic lymphoma with high or low miR-338-3p expression.
| miR-338-3p expression | ||||
|---|---|---|---|---|
| Characteristic | No. of patients (n=38) | Low (n=18) | High (n=20) | P-value |
| Sex | 0.351 | |||
| Male | 28 | 12 | 16 | |
| Female | 10 | 6 | 4 | |
| Age, years | 0.573 | |||
| <40 | 29 | 13 | 16 | |
| >40 | 9 | 5 | 4 | |
| B-symptoms | 0.564 | |||
| Yes | 13 | 7 | 6 | |
| No | 25 | 11 | 14 | |
| BM involvement | 0.184 | |||
| Yes | 9 | 6 | 3 | |
| No | 29 | 12 | 17 | |
| Bulky disease (>10 cm) | 0.018 | |||
| Yes | 22 | 14 | 8 | |
| No | 16 | 4 | 12 | |
| Ann Arbor stage | 0.021 | |||
| I/IE or II/IIE | 11 | 2 | 9 | |
| III/IV | 27 | 16 | 11 | |
| Albumin | 0.351 | |||
| ≤35 g/dl | 10 | 6 | 4 | |
| >35 g/dl | 28 | 12 | 16 | |
| Therapy response | 0.386 | |||
| CR | 27 | 14 | 13 | |
| Not CR | 11 | 4 | 7 | |
| Relapse in 2 years | 0.010 | |||
| Yes | 23 | 7 | 16 | |
| No | 15 | 11 | 4 | |
BM, bone marrow; CR, complete response; miR-338-3p, microRNA-338-3p.