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. 2019 Jul 12;20(3):2633–2640. doi: 10.3892/mmr.2019.10493

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Copyright: © Sui et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effects of Let-7a inhibitor on the expression of inflammatory factors in LPS-treated ATDC5 cells. ATDC5 cells were treated with 5 µg/ml LPS for 5 h after 48 h of transfection with miR-NC inhibitor, Let-7a inhibitor or Let-7a inhibitor + IL-6R-siRNA. ELISA was used to detect the expression of inflammatory factors, including (A) TNF-α, (B) IL-1β, (C) IL-6 and (D) IL-8. Data are presented as the mean ± SD. **P<0.01. Let-7a, microRNA-let7a; LPS, lipopolysaccharide; IL-6R, interleukin 6 receptor; siRNA, small interfering RNA; NC, negative control; TNF-α, tumor necrosis factor α; IL-, interleukin; miR, microRNA.