Table 1.
AUC values of five drug-repurposing methods
| Methods | AUC value for BRCA-derived simulation data avg (min/max) | AUC value for PRAD-derived simulation data avg (min/max) |
|---|---|---|
| CMap | 0.75 (0.58/0.84) | 0.73 (0.66/0.79) |
| sscMap | 0.75 (0.51/0.87) | 0.77 (0.62/0.86) |
| NFFinder | 0.54 (0.52/0.57) | 0.52 (0.50/0.54) |
| Cogenaa | 0.60 | 0.56 |
| Dr Insight | 0.91 b | 0.88 |
a
Cogena has only one AUC value (per simulation data), which is derived from the gene signature selected with the recommended criteria by Cogena paper. bBold values denote the best AUC values across all five methods.