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. 2019 Aug 6;10:1700. doi: 10.3389/fmicb.2019.01700

Figure 1.

Figure 1

Sequence and phylogenetic analysis of CLP1 and its homologs. (A) Schematic diagram of CLP1 containing a conserved C4HC3 PHD finger and a UIM. The yeast CTI6 diagram is also shown. (B) Phylogenetic analysis of CLP1 and its homologs from Trichoderma, Penicillium, Fusarium, Neurospora, and Aspergillus species. The phylogenetic tree was generated with MEGA6. Numbers on the tree branches represent the bootstrap support calculated per 1,000 bootstrap replicates. The sequence identity between CLP1 and its homologs is indicated. (C) Sequence alignment of the PHD in CLP1 and its homologs. The conserved amino acid of C4HC3 motif is indicated by asterisks and the two residues (C145 and H150) to be mutagenized in this study are indicated with red asterisks. (D) Sequence alignment of the UIMs in CLP1 and its homologs.