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. 2019 Jul 9;9(17):5065–5084. doi: 10.7150/thno.34014

Figure 5.

Figure 5

Cdc42 deficiency results in abnormal desmosomes in the epidermis. (A) TEM of the full-thickness dorsal skin of P1 mice. Black arrows indicate intervals between cells in the basal and spinous layer. n = 8 mice per genotype. Ba, basilemma. Scale bars: 2 μm. (B) TEM of the SC, SG and SS of P1 mice. White arrows indicate corneodesmosomes in the SC, and black arrows indicate desmosomes in the SG and SS. (C) Expression and distribution and IF semiquantification of desmoplakin in Cdc42 KO and control mice. n = 8, *p<0.05.