Table 2.
Quantification of E. coli population heterogeneity in steady-state reached for dilution rates of D = 0.1 h−1, 0.36 h−1, and 0.51 h−1, where frozen cells were analyzed at pH 5.5 and 7.
| Parametersa | pH | D = 0.1 h−1 | D = 0.36 h−1 | D = 0.51 h−1 |
|---|---|---|---|---|
| Mean GFP | 7 | 377.5 ± 17.3 | 438.4 ± 4.2 | 422.5 ± 7.1 |
| 5.5 | 359.9 ± 19.3 | 407.8 ± 23.2 | 370.7 ± 14.5 | |
| CV GFP | 7 | 0.24 | 0.28 | 0.29 |
| 5.5 | 0.32 | 0.35 | 0.39 | |
| Peak width | 7 | 262.2 ± 12.5 | 232.7 ± 4.5 | 230.3 ± 5.1 |
| 5.5 | 402.7 ± 9.4 | 419.7 ± 17.9 | 444.0 ± 2.7 | |
| Cdf plot slope | 7 | 0.006 ± 4.8·10−4 | 0.007 ± 6.0·10−4 | 0.006 ± 3.3·10−4 |
| 5.5 | 0.007 ± 2.5·10−4 | 0.007 ± 1.8·10−4 | 0.007 ± 5.7·10−5 | |
| Mode GFP | 7 | 370.3 ± 13.5 | 425.7 ± 4.8 | 415.4 ± 6.3 |
| 5.5 | 385.4 ± 19.3 | 411.3 ± 20.7 | 389.1 ± 15.1 | |
| Skewness GFP | 7 | 9.1 ± 2.7 | 12.4 ± 0.4 | 7.5 ± 0.6 |
| 5.5 | −5.0 ± 0.7 | −2.3 ± 1.8 | −18.7 ± 0.4 |
a
Standard deviations obtained from biological triplicates.