Skip to main content
. 2019 Jul 5;10(8):1122–1127. doi: 10.1021/acsmedchemlett.9b00084

Table 3. Antiproliferative Activities of 10a, 10c, and 10f.

  IC50 (μM)a
compd K562 HL-60 RPMI-8226 HCT-116 A549
10a 0.69 ± 0.21 0.34 ± 0.05 0.36 ± 0.06 1.25 ± 0.07 5.86 ± 0.34
10c 0.49 ± 0.10 0.25 ± 0.01 0.23 ± 0.04 0.83 ± 0.03 0.79 ± 0.07
10f 0.83 ± 0.13 0.61 ± 0.03 0.64 ± 0.06 2.25 ± 0.12 9.45 ± 1.07
SAHA 1.45 ± 0.13 0.52 ± 0.08 0.57 ± 0.06 1.81 ± 0.17 2.42 ± 0.02
a

IC50 values are expressed as the mean ± standard deviation of three separate determinations.