Table 2.
(A): Health utilisation, and (B) health costs per patient 12 months before and after switch, unadjusted and adjusted (=predicted)* n=1620 patients
| (A) Total health utilisation per patient | Unadjusted number, mean (SD) | Adjusted number, mean (95% CI)* | |||
| Preswitch | Post-switch | Preswitch | Postswitch | ||
| Outpatient | Number of outpatient visits | 12.30 (9.40) | 13.31 (9.75) | 9.42 (7.91 to 11.22) | 11.09 (9.34 to 13.16) |
| Inpatient services | Number of inpatient admissions | 0.25 (0.64) | 0.11 (0.40) | 0.15 (0.03 to 0.67) | 0.06 (0.01 to 0.69) |
| Number of days in hospital | 1.19 (5.26) | 0.49 (2.73) | 0.66 (0.06 to 7.25) | 0.20 (0.004 to 10.47) | |
| Medication† | Pain medication | 171 (254) | 170 (250) | 168 (88 to 320) | 165 (86 to 315) |
| Other medication | 937 (1119) | 955 (1135) | 659 (355 to 1223) | 678 (364 to 1262) | |
| Total | 1108 (1225) | 1124 (1241) | 832 (447 to 1549) | 848 (455 to 1584) | |
| (B) Total health costs per patient | Unadjusted average cost, mean (SD) | Adjusted average cost, mean (95% CI)* | |||
| Preswitch, € | Postswitch, € | Preswitch, € | Postswitch, € | ||
| Inpatient services | Diseases of the musculoskeletal system and connective tissue | 315 (1645) | 306 (2330) | 122 (58 to 258) | 385 (144 to 1030) |
| Other diseases | 1014 (4326) | 1121 (4607) | 491 (268 to 902) | 297 (150 to 587) | |
| Total | 1330 (4720) | 1428 (5501) | 660 (355 to 1227) | 500 (255 to 977) | |
| Outpatient services | Diseases of the musculoskeletal system and connective tissue | 4445 (6898) | 4700 (7381) | 4051 (2171 to 7559) | 4040 (2150 to 7589) |
| Other diseases | 860 (2623) | 1069 (3498) | 368 (197 to 688) | 484 (253 to 928) | |
| Total | 5305 (7369) | 5769 (8107) | 4436 (2529 to 7779) | 4593 (2618 to 8059) | |
| Primary sector† | General practitioner | 201 (208) | 208 (218) | 171 (93 to 314) | 174 (95 to 318) |
| Other practicing specialist | 105 (229) | 103 (211) | 98 (53 to 180) | 89 (48 to 164) | |
| Physiotherapist, chiropractor, foot specialist | 397 (807) | 384 (801) | 423 (222 to 807) | 388 (200 to 751) | |
| Other | 75 (112) | 70 (97) | 66 (35 to 124) | 63 (33 to 118) | |
| Total | 778 (936) | 765 (921) | 756 (408 to 1404) | 709 (381 to 1321) | |
| Medication‡ | Pain medication | 75 (239) | 74 (231) | 63 (33 to 119) | 62 (32 to 118) |
| Other medication | 391 (638) | 372 (595) | 255 (136 to 478) | 250 (134 to 466) | |
| Total | 466 (721) | 446 (682) | 321 (172 to 601) | 312 (167 to 584) | |
| Total costs | 7880 (9427) | 8408 (10489) | 6176 (3685 to 10353) | 6264 (3741 to 10491) | |
*Predicted costs are for female, 55 years old, not dead in the postswitch period, not withdrawn SB4 within 0–180 days, previous duration of ETA treatment >5 years and with no previous comorbidities.
†For primary sector, no specific data are available for health utilisation thus only costs are shown.
‡Defined daily dose of medication total costs.