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. 2019 Aug 12;5(2):e001016. doi: 10.1136/rmdopen-2019-001016

Table 4.

Regression model estimating the influence of patient characteristics on (A) changes in health utilisation after switch, and (B) changes in costs after switch. Models include interaction term ‘after’ and adjusting variables†

Interaction term
After*gender (Male=1) After*age/year After*ETA duration‡
Exp (estimate) P value Exp (estimate) P value Exp (estimate) P value
(A) Changes in health utilisation per patient
 Inpatient services Number of inpatient admissions 0.98 (0.64–1.48) 0.907 1.01 (0.99–1.03) 0.208 1.11 (0.97–1.27) 0.136
Number of days in hospital 0.83 (0.40–1.73) 0.622 1.02 (0.99–1.04) 0.200 1.12 (0.87–1.43) 0.392
 Outpatient Number of outpatient visits 1.01 (0.95–1.07) 0.826 1.00 (1.00–1.00) 0.841 1.07 (1.05– 1.19) <0.0001
 Medication Pain medication, DDD 1.01 (0.94–1.09) 0.777 1.00 (0.99–1.00) 0.763 1.01 (0.99–1.04) 0.293
Other medication 0.98 (0.93–1.03) 0.431 1.00 (0.99–1.00) 0.383 1.00 (0.98–1.02) 0.767
Total 0.98 (0.94–1.03) 0.477 1.00 (0.99–1.00) 0.344 1.01 (0.99–1.02) 0.571
(B) Changes in health costs per patient
 Inpatient services Diseases of the musculoskeletal system and connective tissue 0.61 (0.23–1.61) 0.321 1.03 (1.00–1.05) 0.066 1.19 (0.88–1.66) 0.251
Other diseases 0.99 (0.58–1.72) 0.984 1.03 (1.01– 1.05) 0.002 1.00 (0.82–1.21) 0.966
Total 0.97 (0.60–1.58) 0.903 1.03 (1.01– 1.04) 0.002 1.02 (0.87–1.21) 0.784
 Outpatient services Diseases of the musculoskeletal system and connective tissue 1.08 (0.98–1.19) 0.126 1.00 (0.99–1.00) 0.976 1.04 (1.00–1.08) 0.072
Other diseases 1.15 (0.89–1.48) 0.284 1.00 (0.99–1.01) 0.304 1.10 (1.01– 1.19) 0.028
Total 1.08 (0.99–1.18) 0.093 1.00 (1.00–1.00) 0.521 1.04 (1.00– 1.08) 0.036
 Primary sector General practitioner 1.07 (0.98–1.16) 0.153 1.00 (1.00–1.00) 0.682 1.04 (1.01– 1.08) 0.007
Other practicing specialist 1.04 (0.80–1.36) 0.756 1.00 (0.99–1.01) 0.668 0.99 (0.89–1.09) 0.810
Physiotherapist, chiropractor, foot specialist 1.02 (0.91–1.15) 0.705 1.00 (1.00–1.00) 0.256 0.99 (0.95–1.04) 0.754
Other 1.06 (0.90–1.24) 0.484 1.00 (0.99–1.00) 0.719 0.98 (0.92–1.04) 0.465
Total 1.05 (0.98–1.13) 0.176 1.00 (1.00–1.00) 0.423 1.00 (0.98–1.03) 0.769
 Medication§ Pain medication 0.99 (0.88–1.10) 0.823 1.00 (1.00–1.00) 0.957 1.03 (0.99–1.07) 0.119
Other medication 0.94 (0.85–1.04) 0.214 1.00 (0.99–1.00) 0.375 1.00 (0.97–1.04) 0.835
Total 0.96 (0.88–1.04) 0.287 1.00 (1.00–1.00) 0.404 1.01 (0.98–1.03) 0.513
Total costs 1.03 (0.94–1.14) 0.516 1.00 (1.00–1.01) 0.085 1.03 (0.99–1.07) 0.146

Statistically significant results are marked with bold types.

†Adjusted for gender, age, dead in post period, duration of ETA before index date, stopped SB4 treatment within 180 days and comorbidities 12–24 months before index date.

‡ETA duration as categories.

§Medication handled by prescription included (ETA, SB4 not included).